[HTML][HTML] Heat treatment-induced autophagy promotes breast cancer cell invasion and metastasis via TGF-β2-mediated epithelial-mesenchymal transitions

Z Li, C Lu, F Wang, H Guo, Z Wang, H Yin, J Li - PeerJ, 2023 - peerj.com
Background Insufficient thermal ablation can accelerate malignant behaviors and
metastases in some solid tumors, and epithelial-mesenchymal transition (EMT) and …

[HTML][HTML] Insufficient microwave ablation-induced promotion of distant metastasis is suppressed by β-catenin pathway inhibition in breast cancer

P Kong, H Pan, M Yu, L Chen, H Ge, J Zhu, G Ma, L Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Microwave ablation (MWA), a thermal ablation, is an effective treatment for breast cancer.
However, residual breast cancer is still detected. The biological characteristics of residual …

Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends

J Kadkhoda, A Tarighatnia, MR Tohidkia, ND Nader… - Life sciences, 2022 - Elsevier
Breast cancer (BC) has different clinical manifestations due to its diverse mechanism of
action that has created many challenges to choosing appropriate treatment. Recent findings …

[HTML][HTML] Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironment

FL Liu, EP Mo, L Yang, J Du, HS Wang, H Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Transforming growth factor-β1 (TGF-β1) present in tumor microenvironment acts in a
coordinated fashion to either suppress or promote tumor development. However, the …

TGF-β1-activated cancer-associated fibroblasts promote breast cancer invasion, metastasis and epithelial-mesenchymal transition by autophagy or overexpression of …

M Huang, M Fu, J Wang, C Xia, H Zhang… - Biochemical …, 2021 - Elsevier
Cancer-associated fibroblasts (CAFs) play an important role in the initiation, metastasis, and
invasion of breast cancer. However, whether autophagy acts as a tumor promotion …

The multifaceted functions of autophagy in breast cancer development and treatment

NJ Niklaus, I Tokarchuk, M Zbinden, AM Schläfli… - Cells, 2021 - mdpi.com
Macroautophagy (herein referred to as autophagy) is a complex catabolic process
characterized by the formation of double-membrane vesicles called autophagosomes …

TGF-β1 promotes autophagy and inhibits apoptosis in breast cancer by targeting TP63

Y Wang, H Lu, Z Wang, Y Li, X Chen - Frontiers in Oncology, 2022 - frontiersin.org
Background Breast cancer (BC) is a prevalent female cancer, which has high morbidity and
mortality. However, the pathogenesis of BC has not been fully elucidated. Studies have …

Lawsone inhibits the proliferation and metastasis of residual breast cancer cells after microwave ablation by inducing cellular inhibitory autophagy through NCAPG …

F Sun, Y Tong, C Zhang, S Yang, Y Liu, J Ji, Z Yu… - 2023 - researchsquare.com
Microwave ablation (MWA) is increasingly used in clinical treatment and research of breast
cancer, which has good therapeutic effect on primary and metastatic lesions. However …

Inhibition of autophagy enhances heat-induced apoptosis in human non-small cell lung cancer cells through ER stress pathways

WY Xie, XD Zhou, J Yang, LX Chen, DH Ran - Archives of biochemistry …, 2016 - Elsevier
The occurrence and mechanisms of autophagy induced by heat stress are not well known in
lung cancer cells. Here, we have demonstrated that heat stress induces autophagy in A549 …

[HTML][HTML] TGF-β2-induced EMT is dampened by inhibition of autophagy and TNF-α treatment

S Dash, PM Sarashetti, B Rajashekar, R Chowdhury… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) typically develops in a chronic inflammatory setting causal
to release of a plethora of growth factors and cytokines. However, the molecular effect of …