Thiosulfate formation and biodegradation processes link aerobic and anaerobic metabolism
of cysteine. In these reactions, sulfite formed from thiosulfate is oxidized to sulfate while …

Enzymes in the sulfur network generate the signaling molecule, hydrogen sulfide (H2S),
from the amino acids cysteine and homocysteine. Since it is toxic at elevated concentrations …

Hydrogen sulfide (H2S) plays important roles in metabolism and health. Its enzymatic
generation from sulfur-containing amino acids (SAAs) is well characterized. However, the …

Hydrogen sulfide is a cardioprotective signaling molecule but is toxic at elevated
concentrations. Red blood cells can synthesize H 2 S but, lacking organelles, cannot …

A cardioprotectant at low concentrations, H 2 S is a toxin at high concentrations and inhibits
cytochrome c oxidase. A conundrum in H 2 S homeostasis is its fate in red blood cells …

In addition to their role as oxygen transporters, red blood cells (RBCs) contribute to
cardiovascular homeostasis by regulating nitric oxide (NO) metabolism via interaction of …

Abstract Hydrogen sulfide (H 2 S), which is a well-known toxic gas, has been recognized as
a signal molecule as well as a cytoprotectant. It is produced by three enzymes, cystathionine …

Cysteine is one of the two key sulfur‐containing amino acids with important functions in
redox homeostasis, protein functionality and metabolism. Cysteine is taken up by mammals …

Traditionally known as a toxic gas, hydrogen sulfide (H 2 S) is now recognized as an
important biological molecule involved in numerous physiological functions. Like nitric oxide …

Significance: Along with other gasotransmitters nitric oxide (NO) and carbon monoxide,
hydrogen sulfide (H2S) has recently emerged as an important signaling molecule with a …