Cerebral small vessel disease is an important cause of vascular cognitive impairment and
dementia. On brain imaging, discrete lacunar infarcts and/or more diffuse regions of white …

New insights into cerebral small vessel disease and vascular... : Current Opinion in Neurology
New insights into cerebral small vessel disease and vascular cognitive impairment from MRI …

Objective Decline in cognitive function begins by the 40s, and may be related to future
dementia risk. We used data from a community‐representative study to determine whether …

The dynamics of BBB permeability after AIS in humans are not well understood. In the
present study we measured the evolution of BBB permeability after AIS in humans using …

Small vessel disease, a disorder of cerebral microvessels, is an expanding epidemic and a
common cause of stroke and dementia. Despite being almost ubiquitous in brain imaging …

Blood-brain barrier (BBB) disruption has long been recognised as an important early feature
of multiple sclerosis (MS) pathology. Traditionally, this has been seen as a by-product of the …

Background and Purpose—Blood–brain barrier dysfunction may be an early phenomenon
in the development of the small vessel disease, which underlies white matter lesions …

White matter hyperintensities are frequent on neuroimaging of older people and are a key
feature of cerebral small vessel disease. They are commonly attributed to chronic …

Background and Purpose—Cerebral small vessel disease (SVD) is associated with
increased stroke risk and poor stroke outcomes. We aimed to evaluate whether chronic SVD …

Alzheimer's disease (AD) and cerebral small vessel disease (cSVD) are the two main
causes of dementia with blood–brain barrier (BBB) breakdown being a common contributor …