Imbalanced angiogenesis in peripartum cardiomyopathy―diagnostic value of placenta growth factor―

A Mebazaa, MF Seronde, E Gayat, K Tibazarwa… - Circulation …, 2017 - jstage.jst.go.jp
Background: Concentrations of the anti-angiogenic factor soluble fms-like tyrosine kinase-1
(sFlt-1) are altered in peripartum cardiomyopathy (PPCM). In this study we investigated …

Relaxin-2 and soluble Flt1 levels in peripartum cardiomyopathy: results of the multicenter IPAC study

J Damp, MM Givertz, M Semigran, R Alharethi… - JACC: Heart Failure, 2016 - jacc.org
Objectives: This study explored the association of vascular hormones with myocardial
recovery and clinical outcomes in peripartum cardiomyopathy (PPCM). Background: PPCM …

Angiogenic imbalance and residual myocardial injury in recovered peripartum cardiomyopathy patients

S Goland, JM Weinstein, A Zalik… - Circulation: Heart …, 2016 - Am Heart Assoc
Background—Recent studies suggest that angiogenic imbalance during pregnancy may
lead to acute peripartum cardiomyopathy (PPCM). We propose that angiogenic imbalance …

Biomarkers and their relation to cardiac function late after peripartum cardiomyopathy

AS Ersbøll, JP Goetze, M Johansen, MG Hauge… - Journal of Cardiac …, 2021 - Elsevier
Background Angiogenic imbalance involving the placental protein soluble Fms-like tyrosine
kinase-1 (sFlt-1) and cleavage of the nursing-hormone prolactin by the enzyme cathepsin D …

Associations Between Soluble fms‐Like Tyrosine Kinase‐1 and Placental Growth Factor and Disease Severity Among Women With Preterm Eclampsia and …

R Hastie, L Bergman, SP Walker… - Journal of the …, 2022 - Am Heart Assoc
Background The angiogenic factors soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and
placental growth factor (PlGF) are postulated to be pathogenic disease drivers of …

Elevation of plasma placental growth factor in the patients with ischemic cardiomyopathy

T Nakamura, H Funayama, N Kubo, T Yasu… - International journal of …, 2009 - Elsevier
BACKGROUND: Placental growth factor (PlGF), which is a member of the vascular
endothelial growth factor family, stimulates angiogenesis and collateral growth in ischemic …

Maternal and perinatal outcomes associated with extremely high values for the sFlt‐1 (Soluble fms‐Like Tyrosine Kinase 1)/PlGF (Placental Growth Factor) ratio

C Villalaín, I Herraiz, L Valle, M Mendoza… - Journal of the …, 2020 - Am Heart Assoc
Background There is little knowledge about the significance of extremely high values (> 655)
for the ratio of sF lt‐1 (soluble fms‐like tyrosine kinase 1) to Pl GF (placental growth factor) …

Maternal serum placental growth factor at 11–13 weeks' gestation and fetal cardiac defects

E Llurba, A Syngelaki, O Sánchez… - … in obstetrics & …, 2013 - Wiley Online Library
Objective To investigate the relationship between fetal heart defects and maternal serum
placental growth factor (PlGF), a marker of placental angiogenesis. Methods Maternal serum …

An elevated ratio of placental growth factor to soluble fms-like tyrosine kinase-1 predicts adverse outcomes in patients with stable coronary artery disease

T Matsumoto, S Uemura, Y Takeda, M Matsui… - Internal …, 2013 - jstage.jst.go.jp
Objective To investigate the predictive values of placental growth factor (PlGF) and its
endogenous antagonist, soluble fms-like tyrosine kinase-1 (sFlt-1), for the long-term …

Increased placental sFLT1 (soluble fms-like tyrosine kinase receptor-1) drives the antiangiogenic profile of maternal serum preceding preeclampsia but not fetal …

F Gaccioli, U Sovio, S Gong, E Cook… - …, 2023 - Am Heart Assoc
Background: Preeclampsia and fetal growth restriction (FGR) are both associated with an
increased ratio of sFLT1 (soluble fms-like tyrosine kinase-1) to PlGF (placenta growth factor) …