Development of gut inflammation in mice colonized with mucosa-associated bacteria from patients with ulcerative colitis

Z Du, T Hudcovic, J Mrazek, H Kozakova, D Srutkova… - Gut pathogens, 2015 - Springer
Background Disturbances in the intestinal microbial community (ie dysbiosis) or presence of
the microbes with deleterious effects on colonic mucosa has been linked to the …

Intestinal microbiota signatures associated with inflammation history in mice experiencing recurring colitis

D Berry, O Kuzyk, I Rauch, S Heider… - Frontiers in …, 2015 - frontiersin.org
Acute colitis causes alterations in the intestinal microbiota, but the microbiota is thought to
recover after such events. Extreme microbiota alterations are characteristic of human chronic …

Role of colonic microbiota in the pathogenesis of ulcerative colitis

L Pei, Y Ke, H Zhao, L Wang, C Jia, W Liu, Q Fu… - BMC …, 2019 - Springer
Background Recent studies have found gut microbiota to be closely associated with onset
and perpetuation of UC. Currently, studies about gut microbiota have mainly covered …

Microbiota from patients with ulcerative colitis promote colorectal carcinogenesis in mice

Y Tian, L Zuo, B Guan, H Wu, Y He, Z Xu, M Shen, J Hu… - Nutrition, 2022 - Elsevier
Objectives: Long-term ulcerative colitis (UC) is associated with both dysbiosis in intestinal
microbiota and predisposition to colorectal cancer. In this study, we investigated whether …

Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission

MG Rooks, P Veiga, LH Wardwell-Scott… - The ISME …, 2014 - academic.oup.com
Dysregulated immune responses to gut microbes are central to inflammatory bowel disease
(IBD), and gut microbial activity can fuel chronic inflammation. Examining how IBD-directed …

Ecobiotherapy rich in firmicutes decreases susceptibility to colitis in a humanized gnotobiotic mouse model

JM Natividad, MI Pinto-Sanchez… - Inflammatory bowel …, 2015 - academic.oup.com
Background Alterations in the intestinal microbiota, characterized by depletion of anti-
inflammatory bacteria, such as Firmicutes, in patients with ulcerative colitis (UC) have …

Differential susceptibility of the gut microbiota to DSS treatment interferes in the conserved microbiome association in mouse models of colitis and is related to the …

I Khan, Y Bai, N Ullah, G Liu… - Advanced Gut & …, 2022 - Wiley Online Library
Dysbiosis is a well‐known factor in the pathogenesis of inflammatory bowel disease (IBD).
However, the discovery of a conserved microbiome association in colitis is largely unknown …

[HTML][HTML] Functional characterization of inflammatory bowel disease–associated gut dysbiosis in gnotobiotic mice

H Nagao-Kitamoto, AB Shreiner, MG Gillilland III… - Cellular and molecular …, 2016 - Elsevier
Background & Aims Gut dysbiosis is closely involved in the pathogenesis of inflammatory
bowel disease (IBD). However, it remains unclear whether IBD-associated gut dysbiosis …

Compositional changes in the gut mucus microbiota precede the onset of colitis-induced inflammation

M Glymenaki, G Singh, A Brass… - Inflammatory bowel …, 2017 - academic.oup.com
Background Inflammatory bowel disease (IBD) is associated with an inappropriate immune
response to the gut microbiota. Notably, patients with IBD reportedly have alterations in fecal …

Longitudinal microbiome analysis in a dextran sulfate sodium-induced colitis mouse model

H Park, S Yeo, S Kang, CS Huh - Microorganisms, 2021 - mdpi.com
The role of the gut microbiota in the pathogenesis of inflammatory bowel disease (IBD) has
been in focus for decades. Although metagenomic observations in patients/animal colitis …