Genetic studies of schizophrenia: an update

J Chen, F Cao, L Liu, L Wang, X Chen - Neuroscience bulletin, 2015 - Springer
Schizophrenia (SCZ) is a complex and heterogeneous mental disorder that affects about 1%
of global population. In recent years, considerable progress has been made in genetic …

Genetic insight of schizophrenia: past and future perspectives

A Kumar, S Agarwal, SR Phadke, Y Jaiswal - Gene, 2014 - Elsevier
Schizophrenia (SCZ) has a heritability of about 80%, and the search for the genetic basis of
this disease has been frustrating. Because schizophrenia has no distinguishing pathology or …

Molecular genetic studies of schizophrenia: challenges and insights

C Kato, A Petronis, Y Okazaki, M Tochigi… - Neuroscience …, 2002 - Elsevier
Schizophrenia (SCZ) is a mental disease that affects approximately 1% of the population
with life-long devastating consequences. Based on evidence for a major contribution of …

A comprehensive family-based replication study of schizophrenia genes

KA Aberg, Y Liu, J Bukszár, JL McClay… - JAMA …, 2013 - jamanetwork.com
Importance Schizophrenia (SCZ) is a devastating psychiatric condition. Identifying the
specific genetic variants and pathways that increase susceptibility to SCZ is critical to …

Schizophrenia genetics: where next?

Y Kim, S Zerwas, SE Trace, PF Sullivan - Schizophrenia bulletin, 2011 - academic.oup.com
The purpose of this invited review is to summarize the state of genetic research into the
etiology of schizophrenia (SCZ) and to consider options for progress. The fundamental …

Genetics of schizophrenia and other psychotic disorders

E Pepper, AG Cardno - Current Psychiatry Reviews, 2014 - ingentaconnect.com
Research into the genetic basis of schizophrenia is advancing rapidly. This review gives a
broad overview of results from successive phases of studies in this field, linking these with …

The dice are rolling for schizophrenia genetics: A commentary on 'The emperors of the schizophrenia polygene have no clothes' by Crow (2008)

PF Sullivan - Psychological medicine, 2008 - cambridge.org
Professor Tim Crow's impassioned review (Crow, 2008) addresses the question at the heart
of schizophrenia (Scz) genetics: a decade into the genomic era and after at least 28 genome …

Genetics of schizophrenia: historical insights and prevailing evidence

J Van de Leemput, JL Hess, SJ Glatt, MT Tsuang - Advances in genetics, 2016 - Elsevier
Abstract Schizophrenia's (SZ's) heritability and familial transmission have been known for
several decades; however, despite the clear evidence for a genetic component, it has been …

What next in schizophrenia genetics for the psychiatric genomics consortium?

A Corvin, PF Sullivan - Schizophrenia bulletin, 2016 - academic.oup.com
Over the last 8 years the Psychiatric Genomics Consortium (PGC; http://pgc. unc. edu) has
fundamentally changed the landscape for psychiatric genetics research. This has been …

Genetic research in schizophrenia: new tools and future perspectives

L Bertram - Schizophrenia bulletin, 2008 - academic.oup.com
Genetically, schizophrenia is a complex disease whose pathogenesis is likely governed by
a number of different risk factors. While substantial efforts have been made to identify the …