Background: Growing public awareness of chronic pain resulting from illness and injury has
prompted pharmaceutical researchers and drug corporations to create better, more targeted …

Pain is a widespread and growing health problem worldwide that exerts a considerable
social and economic impact on both patients and healthcare systems and, therefore, on …

An important sensation that warns of potential harm to a specific area of the body is pain.
The prevalence of pain-related conditions globally is a significant and growing public health …

Prolonged delivery of analgesic drugs at target sites remains a critical issue for efficient pain
management. The use of nano-carriers has been reported to facilitate applicable delivery of …

The ongoing opioid crisis highlighted the need for non-steroidal anti-inflammatory drugs
(NSAIDs), nonaddictive analgesics against pain, fever, and inflammation. However, NSAIDs …

Abstract According to International Association for the Study of Pain (IASP), the definition of
pain is “an unpleasant sensory and emotional experience associated with actual or potential …

Pain is commonly categorized into two diverse groups: acute pain, characterized by early
onset and last for a very short time; while chronic pain, characterized by a prolonged pain for …

Transdermal administration of analgesic medications offers several benefits over alternative
routes of administration, including a decreased systemic drug load with fewer side effects …

Pain remains a global health challenge affecting approximately 1.5 billion people
worldwide. Pain has been an implicit variable in the equation of human life for many …

Background Pain is a vital sense that indicates the risk of injury at a particular body part.
Successful control of pain is the principal aspect in medical treatment. In recent years, the …