Objective Co-occurrence of behavioral and emotional problems in childhood is widespread,
and previous studies have suggested that this reflects vulnerability to experience a range of …

Objective Associations between psychiatric problems and white matter (WM) microstructure
have been reported in youth. Yet, a deeper understanding of this relation has been …

Importance Many mental disorders emerge during adolescence, which may reflect a cost of
the potential for brain plasticity offered during this period. Brain dysconnectivity has been …

Background One major risk factor for the development of psychopathology is a family history
of psychopathology (FHP). Cross-sectional studies have shown that FHP is associated with …

Importance White matter (WM) abnormalities have been identified in schizophrenia at the
earliest stages of the disorder. Individuals in the general population with psychotic …

Maternal history of depression is a strong predictor of depression in offspring and linked to
structural and functional alterations in the developing brain. However, very little work has …

Background An emerging body of literature has indicated that broad, transdiagnostic
dimensions of psychopathology are associated with alterations in brain structure across the …

Background Genome-wide association studies have identified numerous genetic variants
that predispose to neuropsychiatric traits. Identification of mechanisms in the brain that …

Importance Psychiatric disorders in youth characterized by behavioral and emotional
dysregulation are often comorbid and difficult to distinguish. An alternative approach to …

Objective: Psychiatric symptomatology during childhood predicts persistent mental illness
later in life. While neuroimaging methodologies are routinely applied cross-sectionally to the …