SARS-CoV-2 neutralizing antibody LY-CoV555 in outpatients with Covid-19

P Chen, A Nirula, B Heller, RL Gottlieb… - … England Journal of …, 2021 - Mass Medical Soc
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
coronavirus disease 2019 (Covid-19), which is most frequently mild yet can be severe and …

A neutralizing monoclonal antibody for hospitalized patients with Covid-19

Activ-3/Tico Ly-CoV555 Study … - New England Journal of …, 2021 - Mass Medical Soc
Background LY-CoV555, a neutralizing monoclonal antibody, has been associated with a
decrease in viral load and the frequency of hospitalizations or emergency department visits …

REGN-COV2, a neutralizing antibody cocktail, in outpatients with Covid-19

DM Weinreich, S Sivapalasingam… - … England Journal of …, 2021 - Mass Medical Soc
Background Recent data suggest that complications and death from coronavirus disease
2019 (Covid-19) may be related to high viral loads. Methods In this ongoing, double-blind …

[HTML][HTML] Neutralizing monoclonal antibodies for treatment of COVID-19

PC Taylor, AC Adams, MM Hufford… - Nature Reviews …, 2021 - nature.com
Several neutralizing monoclonal antibodies (mAbs) to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) have been developed and are now under evaluation in clinical …

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

BE Jones, PL Brown-Augsburger, KS Corbett… - Science translational …, 2021 - science.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health
threat for which preventive and therapeutic agents are urgently needed. Neutralizing …

Longitudinal dynamics of the neutralizing antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection

K Wang, QX Long, HJ Deng, J Hu… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) is a global pandemic with no
licensed vaccine or specific antiviral agents for therapy. Little is known about the longitudinal …

The impact of neutralizing monoclonal antibodies on the outcomes of COVID‐19 outpatients: a systematic review and meta‐analysis of randomized controlled trials

WT Lin, SH Hung, CC Lai, CY Wang… - Journal of medical …, 2022 - Wiley Online Library
To assess the clinical efficacy and safety of neutralizing monoclonal antibodies (mABs) for
outpatients with coronavirus disease 2019 (COVID‐19). PubMed, Embase, Web of Science …

Safety, virologic efficacy, and pharmacokinetics of CT-P59, a neutralizing monoclonal antibody against SARS-CoV-2 spike receptor-binding protein: two randomized …

JY Kim, YR Jang, JH Hong, JG Jung, JH Park… - Clinical Therapeutics, 2021 - Elsevier
Purpose Neutralizing antibodies can reduce SARS-CoV-2 cellular entry, viral titers, and
pathologic damage. CT-P59 (regdanvimab), a SARS-CoV-2 neutralizing monoclonal …

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
Prophylactic and therapeutic drugs are urgently needed to combat coronavirus disease
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

SARS-CoV-2 neutralizing antibodies: a network meta-analysis across vaccines

P Rogliani, A Chetta, M Cazzola, L Calzetta - Vaccines, 2021 - mdpi.com
Background: There are no studies providing head-to-head comparison across SARS-CoV-2
vaccines. Therefore, we compared the efficacy of candidate vaccines in inducing …