Psoriatic arthritis from a mechanistic perspective

G Schett, P Rahman, C Ritchlin, IB McInnes… - Nature Reviews …, 2022 - nature.com
Psoriatic arthritis (PsA) is part of a group of closely related clinical phenotypes ('psoriatic
disease') that is defined by shared molecular pathogenesis resulting in excessive …

Immune regulation in psoriasis and psoriatic arthritis—recent developments

AJ Hueber, IB McInnes - Immunology letters, 2007 - Elsevier
Psoriasis and psoriatic arthritis (PsA) are common diseases associated with considerable
morbidity and disability. Their pathophysiology comprises a dysfunctional stromal–immune …

Psoriasis and psoriatic arthritis: clinical features and disease mechanisms

WA Myers, AB Gottlieb, P Mease - Clinics in dermatology, 2006 - Elsevier
Psoriasis is a chronic skin disorder affecting approximately 1% to 3% of the world's
population. A considerable proportion of patients with psoriasis will develop a form of …

Current concepts in psoriatic arthritis: pathogenesis and management.

K De Vlam, AB Gottlieb… - Acta dermato …, 2014 - search.ebscohost.com
Psoriatic arthritis occurs in a subset of psoriasis patients and is therefore commonly
encountered in dermatology practice. Although its exact pathogenesis is unknown, psoriatic …

Immunopathology of psoriasis and psoriatic arthritis

DJ Veale, C Ritchlin, O FitzGerald - Annals of the rheumatic diseases, 2005 - ard.bmj.com
Psoriatic arthritis (PsA) is characterised by several unique clinical features that differentiate it
from rheumatoid arthritis (RA). Attempts to identify immunopathological mechanisms, some …

Etiology and pathogenesis of psoriatic arthritis

JL Barnas, CT Ritchlin - Rheumatic Disease Clinics, 2015 - rheumatic.theclinics.com
Arthritis associated with psoriasis was first described in 1956 by Wright. 1 It was not until
1973, however, that Moll and Wright 2 defined the various clinical phenotypes, including …

The molecular pathophysiology of psoriatic arthritis—the complex interplay between genetic predisposition, epigenetics factors, and the microbiome

AL Carvalho, CM Hedrich - Frontiers in molecular biosciences, 2021 - frontiersin.org
Psoriasis is a symmetric autoimmune/inflammatory disease that primarily affects the skin. In
a significant proportion of cases, it is accompanied by arthritis that can affect any joint, the …

Psoriatic arthritis: pathogenesis and targeted therapies

AB Azuaga, J Ramírez, JD Cañete - International journal of molecular …, 2023 - mdpi.com
Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease
characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and …

Immunomodulation in psoriatic arthritis: focus on cellular and molecular pathways

MS Chimenti, E Ballanti, C Perricone, P Cipriani… - Autoimmunity …, 2013 - Elsevier
Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy associated with psoriasis.
Pathogenesis is incompletely understood and pathophysiological role of synovium is just …

[PDF][PDF] Pathogenesis and treatment of psoriasis: exploiting pathophysiological pathways for precision medicine

W Alwan, FO Nestle - Clin Exp Rheumatol, 2015 - clinexprheumatol.org
Psoriasis is a common, chronic inflammatory skin disease associated with multi-system
manifestations including arthritis and obesity. Our knowledge of the aetiology of the …