The Anp genetic variant Rs5068 and circulating levels of natriuretic peptides in patients with chronic heart failure

V Cannone, S Barlera, S Pileggi… - International …, 2014 - internationaljournalofcardiology.com
Atrial (ANP) and B-type natriuretic peptides (BNPs) are cardiac hormones released by the
heart in response to myocardial stretch and volume overload [1]. ANP and BNP induce …

Visualizing the basis for paracrine natriuretic peptide signaling in human heart

KB Margulies, JC Burnett Jr - Circulation research, 2006 - Am Heart Assoc
Since the discovery of atrial natriuretic factor 25 years ago, 1 there has been an explosion of
research elucidating the basic biology of endogenous natriuretic peptides. Among other …

Genetic polymorphisms of the natriuretic peptide system in the pathogenesis of cardiovascular disease: what lies on the horizon?

C Vassalle, MG Andreassi - Clinical chemistry, 2009 - academic.oup.com
Background: The natriuretic peptide hormone family includes various proteins characterized
by similar chemical structure and shared biological functions, with important effects on the …

Impact of Natriuretic Peptide Clearance Receptor (NPR3) Gene Variants on Blood Pressure in Type 2 Diabetes

PJ Saulnier, R Roussel, JM Halimi, J Lebrec… - Diabetes …, 2011 - Am Diabetes Assoc
OBJECTIVE Hypertension in diabetes is characterized by abnormal sodium homeostasis,
suggesting a particular role of natriuretic peptide pathway. Natriuretic peptides can affect …

Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites

NL Pereira, N Tosakulwong, CG Scott… - Circulation …, 2015 - Am Heart Assoc
Background—The goal of this study was to identify genetic determinants of plasma N-
terminal proatrial natriuretic peptide (NT-proANP) in the general community by performing a …

The effect of the brain-type natriuretic peptide single-nucleotide polymorphism rs198389 on test characteristics of common assays

LC Costello-Boerrigter, G Boerrigter… - Mayo Clinic …, 2011 - Elsevier
OBJECTIVE To assess in a US general adult population the effect of the functional single-
nucleotide polymorphism rs198389 in the promoter region of the gene of brain-type …

Systematic screening of type B human natriuretic peptide receptor gene polymorphisms and association with essential hypertension

D Rahmutula, T Nakayama, M Soma, M Sato… - Journal of human …, 2001 - nature.com
C-type natriuretic peptide (CNP) dilates arteries, lowers blood pressure and inhibits
proliferation of vascular smooth muscle cells via the type B natriuretic peptide receptor …

Natriuretic Peptide Receptors (NPRs) as a Potential Target for the Treatment of Heart Failure

AT Bekele - Current Heart Failure Reports, 2023 - Springer
Abstract Purpose of Review Heart failure is defined as a complex clinical syndrome that
results from any structural or functional impairment of ventricular filling or ejection of blood …

A C2077T polymorphism of the type B human natriuretic peptide receptor gene is not associated with myocardial infarction.

D Rahmutula, T Nakayama, M Soma… - … Medical Journal of …, 2000 - europepmc.org
Results The distribution of C2077T polymorphism genotypes in the MI patients (CC: CT: TT,
47.2%: 41.1%: 11.7%) was not significantly different from that in the control patients (CC: CT …

Recent advances in natriuretic peptide family genes and cardiovascular diseases

ZJ Wu, W Jin, FR Zhang, Y Liu - Yi Chuan= Hereditas, 2012 - europepmc.org
Natriuretic peptide family consists of several hormones produced by cardiomyocyte,
including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type …