Natriuretic peptides (NP) represent a family of structurally homologous but genetically
distinct peptide hormones involved in regulation of fluid and electrolyte balance, blood …

Background—Natriuretic peptides play a critical role in the maintenance of salt and water
homeostasis and regulation of vascular tone. Thus, interindividual variation in plasma …

What is known and objective Essential hypertension (EH) is a common disease exhibiting
large individual difference in occurrence, development and treatment response. Genetic …

The natriuretic peptide (NP) family is involved in regulation of blood pressure and fluid
volume. We recently characterized the exon/intron organization of the human type A NP …

Heart failure is a leading cause of morbidity and mortality,. Elevated intracardiac pressures
and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic …

Background The polymorphisms rs198358, rs5068 and rs632793 in the natriuretic peptide
precursor A–B gene region [encoding atrial natriuretic peptides (ANP) and brain natriuretic …

Recent studies suggest that the ANP (atrial natriuretic peptide)/NPRA (type A natriuretic
peptide receptor) system modulates ventricular remodelling and cardiac hypertrophy in …

Aims BNP has important effects on haemodynamics and myocardial remodelling which are
protective from development and progression of heart failure. The aim of this study was to …

Background: ANP (atrial natriuretic peptide), acting through NPR1 (natriuretic peptide
receptor 1), provokes hypotension. Such hypotension is thought to be due to ANP inducing …

Natriuretic peptides (NPs) represent a critical pathway in heart failure (HF). We explored
genetic determinants of pharmacodynamic effects of B-type NP (BNP) and changes in …