A map of the transcriptional organization of genes of an organism is a basic tool that is necessary to understand and facilitate a more accurate genetic manipulation of the …
EJR Peterson, DJ Reiss, S Turkarslan… - Nucleic acids …, 2014 - academic.oup.com
The resilience of Mycobacterium tuberculosis (MTB) is largely due to its ability to effectively counteract and even take advantage of the hostile environments of a host. In order to …
G Rehren, S Walters, P Fontan, I Smith, AM Zárraga - Tuberculosis, 2007 - Elsevier
The high sequence identity among the Mycobacterium bovis and Mycobacterium tuberculosis genomes contrasts with the physiological differences reported between these …
Background Mycobacterium tuberculosis senses and responds to the shifting and hostile landscape of the host. To characterize the underlying intertwined gene regulatory network …
SK Ward, B Abomoelak, SA Marcus… - Frontiers in …, 2010 - frontiersin.org
Infection with Mycobacterium tuberculosis, the causative agent of tuberculosis, is considered one of the biggest infectious disease killers worldwide. A significant amount of attention has …
AM Dinan, P Tong, AJ Lohan, KM Conlon… - MBio, 2014 - Am Soc Microbiol
Related species are often used to understand the molecular underpinning of virulence through examination of a shared set of biological features attributable to a core genome of …
D Alland, TS Whittam, MB Murray, MD Cave… - Journal of …, 2003 - Am Soc Microbiol
The comparative-genomic sequencing of two Mycobacterium tuberculosis strains enabled us to identify single nucleotide polymorphism (SNP) markers for studies of evolution …
Abstract Mycobacterium tuberculosis (MTB) infects 30% of all humans and kills someone every 20–30 s. Here we report genome-wide binding for~ 80% of all predicted MTB …
Epigenetics denotes to study the heritable changes occurred in the gene function without any changes in DNA sequence. These epigenetic changes are known to be governed by …