purpose. The liver is the most common site of systemic metastases from uveal melanoma
(UM). Such metastases usually continue to develop despite the application of current …

Purpose To screen the microarray expression of CDH1, ECM1, EIF1B, FXR1, HTR2B, ID2,
LMCD1, LTA4H, MTUS1, RAB31, ROBO1, and SATB1 genes which are predictive of primary …

Background Uveal melanoma is an aggressive cancer which has a high percentage
metastasizing to the liver, with a worse prognosis. Identification of patients at high risk of …

Uveal melanoma (UM) is the most common intraocular tumor worldwide. We proposed to
identify a vital gene signature that has prognostic value for UM metastasis. For this purpose …

Simple Summary Uveal melanoma (UM) is a rare aggressive eye cancer. Although
treatment of the eye tumour is successful, about 50% of UM patients develop a relapse of …

purpose. Incurable metastases develop in approximately 50% of patients with uveal
melanoma (UM). The purpose of this study was to analyze genomic profiles in a large series …

Uveal melanomas frequently metastasize and cause patient death. Many clinical,
histopathologic, molecular, and genetic factors have been linked to metastasis. We …

The molecular analysis of cancer has benefited tremendously from the sequencing of the
human genome integrated with the science of bioinformatics. Microarray analysis …

Tumor heterogeneity is a major obstacle to the success of cancer treatment. An accurate
understanding and recognition of tumor heterogeneity is critical in the clinical management …

Uveal melanoma arises from melanocytes located in the uveal tract of the eye and is the
most common primary intraocular tumor in adults. Metastatic liver disease is the …