Studies using low-resolution methods to assess gene expression during preimplantation
mouse development indicate that changes in gene expression either precede or occur …

The preimplantation development of the mammalian embryo encompasses a series of
critical events: the transition from oocyte to embryo, the first cell divisions, the establishment …

Little is known about gene action in the preimplantation events that initiate mammalian
development. Based on cDNA collections made from each stage from egg to blastocyst …

Culture of preimplantation embryos affects gene expression. The magnitude of the effect on
the global pattern of gene expression, however, is not known. We compared global patterns …

Pre-implantation embryo development is an intricate and precisely regulated process
orchestrated by maternally inherited proteins and newly synthesized proteins following …

Preimplantation development is marked by four major events: the transition of maternal
transcripts to zygotic transcripts, compaction, the first lineage differentiation into inner cell …

Successful human development is dependent upon a cascade of events following
fertilization. Unfortunately, knowledge of these critical events in humans is remarkably …

Background During mammalian pre-implantation embryonic development dramatic and
orchestrated changes occur in gene transcription. The identification of the complete changes …

The mouse embryo is the canonical model for mammalian preimplantation development.
Recent advances in single cell profiling allow detailed analysis of embryogenesis in other …

During mouse preimplantation embryo development, totipotent blastomeres generate the
first three cell lineages of the embryo: trophectoderm, epiblast and primitive endoderm. In …