It was recently reported that increased SOX9 expression drives tumor growth and promotes
cancer invasion during human tumorigenicity and metastasis. However, the prognostic value …

Objective The aim of the this study was to analyze the status of sex-determining region Y-
related high-mobility group box 4 (SOX4) expression in varied human cancers and its …

Background: Many studies have been done to reported the value of SRY-related HMG-box
Gene 2 (SOX2) in prognosis of solid tumors. But results were not particularly consistent …

BACKGROUND SOX2 is a regulator of pluripotent cellular transcription, yet it has been
recently integrated in cancer biology. The present study provides an analytic insight into the …

SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and
contains a high-mobility group (HMG) domain, which permits highly specific DNA binding …

Objective SOX9 plays an important role in bone formation and tumorigenesis. However, its
involvement in osteosarcoma is still unclear. The aim of this study was to investigate the …

Deregulation of SOX9 expression has been detected in various human cancer tissues;
however, the functional role of SOX9 expression has not been fully elucidated in glioma …

Gastric cancer is one of the most frequent tumours and the third leading cause of cancer‐
related death worldwide. The investigation of new biomarkers that can predict patient …

Background: Novel molecular markers are important diagnostic tools for the assessment of
cancer progression and evaluation of effectiveness of the treatment. SOX9, a key regulator …

The embryonic development of neural crest cells and subsequent tissue differentiation are
intricately regulated by specific transcription factors. Among these, SOX10, a member of the …