Differential expression of microRNAs in peripheral blood mononuclear cells identifies autophagy and TGF-beta-related signatures aberrantly expressed in …

A Mohammadi, OB Kelly, M Filice… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims MicroRNAs [miRNAs] have emerged as important regulators
in inflammatory bowel disease [IBD]. This study investigated differential expression of …

Deep dive into microRNAs in inflammatory bowel disease

J Alfaifi, A Germain, AC Heba, D Arnone… - Inflammatory Bowel …, 2023 - academic.oup.com
Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is
thought to develop in genetically predisposed individuals as a consequence of complex …

Whole blood profiling of T-cell-derived microRNA allows the development of prognostic models in inflammatory bowel disease

R Kalla, AT Adams, NT Ventham… - Journal of Crohn's …, 2020 - academic.oup.com
Background MicroRNAs [miRNAs] are cell-specific small non-coding RNAs that can regulate
gene expression and have been implicated in inflammatory bowel disease [IBD] …

Overexpression of miR-595 and miR-1246 in the sera of patients with active forms of inflammatory bowel disease

GW Krissansen, Y Yang, FM McQueen… - Inflammatory bowel …, 2015 - academic.oup.com
Background MicroRNAs (miRNAs) are dysregulated in the inflammatory bowel diseases,
Crohn's disease (CD) and ulcerative colitis (UC), which arise due to dysfunctional host …

MicroRNAs expression in the ileal pouch of patients with ulcerative colitis is robustly up-regulated and correlates with disease phenotypes

S Ben-Shachar, H Yanai, H Sherman Horev, H Elad… - PLoS …, 2016 - journals.plos.org
Background Gene expression alterations are associated with disease behavior in
inflammatory bowel disease (IBD). microRNAs (miRNAs) are dominant in the regulation of …

Functional implications of microRNAs in Crohn's disease revealed by integrating microRNA and messenger RNA expression profiling

O Palmieri, TM Creanza, F Bossa, T Latiano… - International journal of …, 2017 - mdpi.com
Crohn's disease (CD) is a debilitating inflammatory bowel disease (IBD) that emerges due to
the influence of genetic and environmental factors. microRNAs (miRNAs) have been …

Differential miRNA expression in ileal and colonic tissues reveals an altered immunoregulatory molecular profile in individuals with Crohn's disease versus healthy …

A Mohammadi, OB Kelly, MI Smith… - Journal of Crohn's …, 2019 - academic.oup.com
Background MicroRNAs [miRNAs] are key modulators of gene expression in Crohn's
disease [CD] and may drive tissue-specific molecular alterations underlying CD …

MicroRNA and gut microbiota: Tiny but mighty—Novel insights into their cross-talk in inflammatory bowel disease pathogenesis and therapeutics

M Casado-Bedmar, E Viennois - Journal of Crohn's and Colitis, 2022 - academic.oup.com
Abstract MicroRNAs [miRNAs], small non-coding RNAs, have recently been described as
crucial contributors to intestinal homeostasis. They can interact with the gut microbiota in a …

Fecal MicroRNAs show promise as noninvasive Crohn's disease biomarkers

CT Wohnhaas, R Schmid, M Rolser, E Kaaru… - Crohn's & colitis …, 2020 - academic.oup.com
Background Short non-coding microRNAs (miRNAs) are involved in various cellular
processes during disease progression of Crohn's disease (CD) and remarkably stable in …

MicroRNA signatures differentiate Crohn's disease from ulcerative colitis

JS Schaefer, T Attumi, AR Opekun, B Abraham, J Hou… - BMC immunology, 2015 - Springer
Background Excessive and inappropriate immune responses are the hallmark of several
autoimmune disorders, including the inflammatory bowel diseases (IBD): Crohn's disease …