Finding a simple and effective way for transferring cells to the brain lesion site with minimum
side effects mounts a challenge in cell therapy. Cell delivery via nasal route using the …

Extracellular vesicles (EVs) are gaining tremendous importance in comprehending central
nervous system (CNS) function and treating neurological disorders because of their role in …

Extracellular vesicles (EVs) include a heterogeneous group of natural cell-derived
nanostructures that are increasingly regarded as promising biotherapeutic agents and drug …

One of the most challenging problems facing modern medicine is how to deliver a given
drug to a specific target at the exclusion of other regions. For example, a variety of …

Small extracellular vesicles (sEVs) have∼ 30–200 nm diameter size and may act as carriers
of different cargoes, depending on the cell of origin or on the physiological/pathological …

With the recent advancements in development of complex formulations as well as complex
active pharmaceutical ingredient, the route of administration is playing an important role …

Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) are able to carry genetic
and protein goods to mediate the interaction between MSCs and target cells. Recently, more …

Neural stem cell (NSC) grafting in conditions such as aging, brain injury, and
neurodegenerative diseases promotes regeneration, plasticity and functional recovery …

Stem cells such as mesenchymal stem cells (MSCs) enhance neurological recovery in
preclinical stroke models by secreting extracellular vesicles (EVs). Since previous reports …

Abstract Background Neural stem cells (NSCs) have the ability to generate a variety of
functional neural cell types and have a high potential for neuronal cell regeneration and …