Objective: The authors sought to demonstrate that schizophrenia is a heterogeneous group
of heritable disorders caused by different genotypic networks that cause distinct clinical …

Today multinational studies using genome-wide association scan (GWAS) for> 1000, 000
polymorphisms on> 100,000 cases with major psychiatric diseases versus controls …

Schizophrenia is a chronic and severe psychiatric disorder that is highly heritable. While
both common and rare genetic variants contribute to disease risk, many questions still …

Unlike the typical analysis of single markers in genome-wide association studies (GWAS),
we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and …

BACKGROUND:: Genetic epidemiologic studies suggest that individual variation in
susceptibility to schizophrenia is substantially genetic. However, like other common …

Schizophrenia is a common disorder with a high heritability, but its genetic architecture is
still elusive. We implemented whole-genome sequencing (WGS) analysis of 8 families with …

Schizophrenia is a highly heritable, polygenic disorder. A growing list of common genetic
variants have been associated with schizophrenia; there is a clear need to understand the …

The past decade has witnessed major advances in our understanding of the genetics of
schizophrenia. Large, consortia-led genomic studies involving thousands of patients and …

Schizophrenia is a common polygenetic disease affecting 0.5–1% of individuals across
distinct ethnic populations. PGC-II, the largest genome-wide association study investigating …

The genetic etiology of schizophrenia, a common and debilitating psychiatric disorder, is
supported by a wealth of data. Review of the current findings suggests that considerable …