Highlights•The genetic liability of schizophrenia is established as polygenic.•Schizophrenia
risk alleles converge onto specific synaptic gene-sets.•Schizophrenia shares risk alleles with …

Schizophrenia and bipolar disorder have a largely unknown pathophysiology and etiology,
but they are highly heritable. Although linkage and association studies have identified a …

Genomic studies have identified hundreds of candidate genes near loci associated with risk
for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologs …

The importance of genomic copy number variants (CNVs) has long been recognized in the
etiology of neurodevelopmental diseases. We report here the results from the CNV analysis …

SZGR 2.0 is a comprehensive resource of candidate variants and genes for schizophrenia,
covering genetic, epigenetic, transcriptomic, translational and many other types of evidence …

Objective Structural variations of DNA, such as copy number variations (CNVs), are
recognized to contribute both to normal genomic variability and to risk for human diseases …

Schizophrenia (SZ) and bipolar disorder (BPD) have high heritabilities and are clinically and
genetically complex. Genome wide association studies (GWAS) and studies of copy number …

Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk
globally. Large-scale schizophrenia genetic studies have reported primarily on European …

Genome-wide association studies (GWAS) have identified a large number of gene variants
associated with schizophrenia, but these variants explain only a small portion of the …

Since 2006, genome-wide association studies of schizophrenia have led to the identification
of numerous novel risk loci for this disease. However, there remains a geographical …