[HTML][HTML] The long non-coding RNA H19 promotes cardiomyocyte apoptosis in dilated cardiomyopathy

Y Zhang, M Zhang, W Xu, J Chen, X Zhou - Oncotarget, 2017 - ncbi.nlm.nih.gov
In the previous study, we generated a rat model of dilated cardiomyopathy (DCM) induced
by adriamycin and found that the expression of lncRNA H19 was significantly upregulated in …

[HTML][HTML] Knockdown of lncRNA MALAT1 attenuates acute myocardial infarction through miR-320-Pten axis

H Hu, J Wu, D Li, J Zhou, H Yu, L Ma - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Abstract Background Long noncoding RNA (LncRNA) metastasis-associated lung
adenocarcinoma transcript 1 (MALAT1) is involved in the development of acute myocardial …

LncRNA MALAT1 protects cardiomyocytes from isoproterenol‐induced apoptosis through sponging miR‐558 to enhance ULK1‐mediated protective autophagy

X Guo, X Wu, Y Han, E Tian… - Journal of Cellular …, 2019 - Wiley Online Library
Investigating the molecular mechanisms of myocardial infarction (MI) and subsequent heart
failure have gained considerable attention worldwide. Long noncoding RNA (lncRNA) …

TMEM11 regulates cardiomyocyte proliferation and cardiac repair via METTL1-mediated m7G methylation of ATF5 mRNA

XZ Chen, XM Li, SJ Xu, S Hu, T Wang, RF Li… - Cell Death & …, 2023 - nature.com
The mitochondrial transmembrane (TMEM) protein family has several essential
physiological functions. However, its roles in cardiomyocyte proliferation and cardiac …

Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m6A Modification of MAT2A Pre‐mRNA by METTL16

PB Chen, GX Shi, T Liu, B Li, SD Jiang… - Oxidative Medicine …, 2022 - Wiley Online Library
The process of intervertebral disc degeneration (IVDD) is complex, and its mechanism is
considered multifactorial. Apoptosis of oxidative stressed nucleus pulposus cells (NPCs) …

Melatonin alleviates cardiac fibrosis via inhibiting lncRNA MALAT1/miR‐141‐mediated NLRP3 inflammasome and TGF‐β1/Smads signaling in diabetic …

H Che, Y Wang, H Li, Y Li, A Sahil, J Lv… - The FASEB …, 2020 - Wiley Online Library
Melatonin is a hormone produced by the pineal gland, and it has extensive beneficial effects
on various tissue and organs; however, whether melatonin has any effect on cardiac fibrosis …

[HTML][HTML] LncRNA H19 inhibits autophagy by epigenetically silencing of DIRAS3 in diabetic cardiomyopathy

C Zhuo, R Jiang, X Lin, M Shao - Oncotarget, 2017 - ncbi.nlm.nih.gov
We previously generated a rat model of diabetic cardiomyopathy and found that the
expression of long non-coding RNA H19 was downregulated. The present study was aimed …

LncRNA-antisense non-coding RNA in the INK4 locus promotes pyroptosis via miR-497/thioredoxin-interacting protein axis in diabetic nephropathy

J Wang, SM Zhao - Life sciences, 2021 - Elsevier
Aims Diabetic nephropathy (DN) is the most frequent complication of diabetes and causes
millions of deaths each year. Finding novel therapy to DN is urgent, which requires a good …

CircRNA CDR1as promotes cardiomyocyte apoptosis through activating hippo signaling pathway in diabetic cardiomyopathy

Y Shao, M Li, Q Yu, M Gong, Y Wang, X Yang… - European journal of …, 2022 - Elsevier
Diabetic cardiomyopathy (DCM), as a major complication of diabetic patients, can cause
myocardial metabolic remodeling and lead to severe and irreversible cardiac dysfunction …

WTAP-mediated N6-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy

J Lan, B Xu, X Shi, Q Pan, Q Tao - Cellular & Molecular Biology Letters, 2022 - Springer
Background Diabetic nephropathy (DN) is prevalent in patients with diabetes. N 6-
methyladenosine (m6A) methylation has been found to cause modification of nucleotide …