Background and objectives Peptic ulcer disease, chronic gastritis, and stomach cancer are
all caused by H. pylori. The most notable drug for the treatment is the antibiotic …

To determine the 23S rRNA point mutations in clarithromycin resistance of Helicobacter
pylori strains isolated from southwest, Iran. This was a cross-sectional survey, which was …

Background: Clarithromycin resistance in Helicbacter pylori has been found to be
associated with point mutations in 23s rRNA gene leads to reduced affinity of the antibiotic to …

Background Helicobacter pylori is an important pathogen of human gastric mucosa.
Antibiotic resistance, especially resistance to clarithromycin is a major factor for treatment …

Background: Helicobacter pylori is curved Gram negative and microaerophilic bacilli that
have infected half of the world's population. It is recognized as the causative agent of …

Polymerase chain reaction (PCR) for detection of single nucleotide mutations in 23S rRNA
gene of clarithromycin resistance Helicobacter pylori were investigated worldwide. In …

Background: Helicobacter pylori antimicrobial resistance is an important factor responsible
for treatment failure. The purpose of this study was evaluating the prevalence of point …

Purpose. We aimed to investigate the presence of three recently identified point mutations
(A2115G, G2141A and A2144T) of the 23 S rRNA gene and compare them with the three …

Antibiotic resistance has brought into question the efficiency of clarithromycin which is a vital
component of eradication therapy for Helicobacter pylori infection. The point mutations …

This study aimed to investigate the clarithromycin resistance and its associated molecular
mechanisms among Helicobacter pylori isolates from dyspeptic patients in Shiraz, Iran. From …