Decrease of serum S100B during an oral glucose tolerance test correlates inversely with the insulin response

J Steiner, HG Bernstein, K Schiltz, T Haase… - …, 2014 - Elsevier
Increased S100B serum levels have been considered as a marker of glial pathology, brain
damage, and blood–brain-barrier impairment. However, S100B expression has also been …

Serum levels of S100B are decreased in chronic starvation and normalize with weight gain

K Holtkamp, K Bühren, G Ponath, C von Eiff… - Journal of Neural …, 2008 - Springer
S100B protein is mainly synthesized in glial cells and modulates the balance between cell
proliferation and differentiation in neurons and glial cells. However, S100B is not CNS …

S100B serum levels are closely correlated with body mass index: an important caveat in neuropsychiatric research

J Steiner, K Schiltz, M Walter, MT Wunderlich… - …, 2010 - Elsevier
Elevated blood levels of S100B in neuropsychiatric disorders have so far been mainly
attributed to glial pathologies. However, increases or dysfunction of adipose tissue may be …

Extracranial sources of S100B do not affect serum levels

N Pham, V Fazio, L Cucullo, Q Teng, P Biberthaler… - PloS one, 2010 - journals.plos.org
S100B, established as prevalent protein of the central nervous system, is a peripheral
biomarker for blood-brain barrier disruption and often also a marker of brain injury. However …

[HTML][HTML] Levels of serum S100B are associated with cognitive dysfunction in patients with type 2 diabetes

H Yu, H Li, X Liu, X Du, B Deng - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Objective: Previous studies have provided robust evidence that cognitive impairment exists
in patients with type 2 diabetes. The predictive role of S100B in a variety of …

[HTML][HTML] Hyper-glycemia and insulinemia induce morphological changes and modulate secretion of S100B, S100A8, amyloid β 1–40 and amyloid β 1–42, in a model …

A Kubis-Kubiak, B Wiatrak, A Piwowar - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Glucose metabolism in neuronal tissue declines during neurodegenerative disorders in a
progressive, region-specific, and disease-specific manner. Studies have shown that …

Serum S100B protein is increased in fasting rats

CBO Netto, S Conte, MC Leite, C Pires… - Archives of medical …, 2006 - Elsevier
BACKGROUND: S100B is a calcium-binding protein expressed and secreted by astrocytes;
serum and cerebrospinal fluid (CSF) S100B elevation has been proposed as an index of …

The Multifaceted S100B Protein: A Role in Obesity and Diabetes?

F Michetti, G Di Sante, ME Clementi, F Valeriani… - International Journal of …, 2024 - mdpi.com
The S100B protein is abundant in the nervous system, mainly in astrocytes, and is also
present in other districts. Among these, the adipose tissue is a site of concentration for the …

Adipocytes as an important source of serum S100B and possible roles of this protein in adipose tissue

CA Gonçalves, MC Leite… - … psychiatry and neurology, 2010 - Wiley Online Library
Adipocytes contain high levels of S100B and in vitro assays indicate a modulated secretion
of this protein by hormones that regulate lipolysis, such as glucagon, adrenaline, and …

S100B is expressed in, and released from, OLN-93 oligodendrocytes: influence of serum and glucose deprivation

J Steiner, HG Bernstein, B Bogerts, T Gos… - Neuroscience, 2008 - Elsevier
S100B (member of a family of proteins that are 100% soluble in ammonium sulfate at neutral
pH) has been widely used as astrocyte marker in animal models and in human brain …