Molnupiravir efficacy among immunocompromised patients with COVID-19: no proof of concept

D Guermazi, P Arvanitis, D Farmakiotis - Infection, 2023 - Springer
We read with interest the study “Molnupiravir for the treatment of COVID-19 in
immunocompromised participants: efficacy, safety, and virology results from the phase 3 …

[HTML][HTML] The effect of molnupiravir on post-acute outcome of COVID-19 survivors

WH Hsu, BW Shiau, YW Tsai, JY Wu, TH Liu… - The Journal of …, 2023 - ncbi.nlm.nih.gov
We read with great interest the review article by Gary et al., in which they raised several
concerns about the use of molnupiravir in the treatment of patients with COVID-19. 1 At the …

Molnupiravir for the treatment of COVID-19 in immunocompromised participants: efficacy, safety, and virology results from the phase 3 randomized, placebo-controlled …

MG Johnson, JM Strizki, ML Brown, H Wan… - Infection, 2023 - Springer
Purpose Immunocompromised patients have a potentially increased risk for progression to
severe COVID-19 and prolonged replication of SARS-CoV-2. This post hoc analysis …

Molnupiravir for the treatment of non-severe COVID-19: a systematic review and meta-analysis of 14 randomized trials with 34 570 patients–authors' response

M Sun, H Lai, Z Zhang, L Ge - Journal of Antimicrobial …, 2023 - academic.oup.com
We thank Drs Kow, Ramachandram and Hasan for their interest in our review and their
knowledgeable comments. 1 We agree with your thoughtful view that the most important …

Comment on: Molnupiravir for the treatment of non-severe COVID-19: a systematic review and meta-analysis of 14 randomized trials with 34 570 patients

IW Chen, LC Chang, KC Hung - Journal of Antimicrobial …, 2024 - academic.oup.com
We read with great interest the systematic review and meta-analysis by Sun et al. 1 titled
'Molnupiravir for the treatment of non-severe COVID-19: a systematic review and meta …

Is molnupiravir a wise investment? Reassessing COVID-19 treatment strategies

CS Kow, DS Ramachandram… - Journal of Antimicrobial …, 2023 - academic.oup.com
We were greatly intrigued by the systematic review and meta-analysis conducted by Sun et
al., 1 which investigated the efficacy of molnupiravir in patients with COVID-19. As we find …

Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … England Journal of …, 2022 - Mass Medical Soc
Background New treatments are needed to reduce the risk of progression of coronavirus
disease 2019 (Covid-19). Molnupiravir is an oral, small-molecule antiviral prodrug that is …

528. Matched retrospective study, comparing molnupiravir to nirmatrelvir-ritonavir (Paxlovid) in the treatment of mild-moderate COVID-19 in immunocompromised …

A Haddad, M Moussa, RY Hachem… - Open Forum …, 2023 - academic.oup.com
Background Paxlovid has been shown to reduce the risk of progression
(hospitalization/death) by 88% as compared to placebo, while molnupiravir reduced that risk …

Randomized trial of molnupiravir or placebo in patients hospitalized with Covid-19

JR Arribas, S Bhagani, SM Lobo, I Khaertynova… - NEJM …, 2022 - evidence.nejm.org
Background Molnupiravir is an oral prodrug of β-d-N4-hydroxycytidine, active against SARS-
CoV-2 in vitro and in animal models. We report data from the phase 2 component of MOVe …

Efficacy and safety of molnupiravir for the treatment of SARS-CoV-2 infection: a systematic review and meta-analysis

JJ Malin, S Weibel, H Gruell… - Journal of …, 2023 - academic.oup.com
Background The role of molnupiravir for coronavirus disease 2019 (COVID-19) treatment is
unclear. Methods We conducted a systematic review until 1 November 2022 searching for …