Background The prevalence and characteristics of pulmonary hypertension in adults with
sickle cell disease have not been clearly established. Methods In this prospective study, we …

Background The prevalence of pulmonary hypertension in adults with sickle cell disease,
the mechanism of its development, and its prospective prognostic significance are unknown …

Recent studies have recognised the importance of pulmonary hypertension (PH) in sickle
cell disease (SCD). The aim of this study was to determine the prevalence and prognostic …

PERSPECTIVE tone, and vascular proliferation in the muscle wall. An associated
hypercoagulable state causes pulmonary thrombosis of the constricted vessels, resulting in …

Rationale: Although pulmonary hypertension (PH) is a common complication of sickle cell
disease (SCD) associated with high mortality, there exist few data characterizing …

Few results on cardiac catheterization have been published for patients with sickle cell
disease (SCD) with pulmonary hypertension (PHTN). Their survival once this complication …

BACKGROUND: Recurrent vaso-occlusive episodes lead to progressive end-organ damage
in patients with sickle cell disease. We sought to determine the prevalence of pulmonary …

The prevalence of pulmonary hypertension (PHTN) in the pediatric sickle cell disease (SCD)
population is not known despite its high prevalence in adult patients. Our hypothesis was …

Background The role of pulmonary hypertension as a cause of mortality in sickle cell
disease (SCD) is controversial. Methods and Results We evaluated the relationship …

Background: Pulmonary hypertension (PH) in adults with sickle cell disease (SCD) is
associated with early mortality, but no prior studies have evaluated quantitative relationships …