[HTML][HTML] Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly
Q Mo, Z Xu, F Deng, H Wang, YJ Ning - PLoS pathogens, 2020 - journals.plos.org
Bunyavirus ribonucleoprotein (RNP) that is assembled by polymerized nucleoproteins (N)
coating a viral RNA and associating with a viral polymerase can be both the RNA synthesis …
coating a viral RNA and associating with a viral polymerase can be both the RNA synthesis …
Bunyamwera virus possesses a distinct nucleocapsid protein to facilitate genome encapsidation
B Li, Q Wang, X Pan… - Proceedings of the …, 2013 - National Acad Sciences
Bunyamwera virus (BUNV), which belongs to the genus Orthobunyavirus, is the prototypical
virus of the Bunyaviridae family. Similar to other negative-sense single-stranded RNA …
virus of the Bunyaviridae family. Similar to other negative-sense single-stranded RNA …
[HTML][HTML] Host cell restriction factors of Bunyaviruses and viral countermeasures
S Lerolle, N Freitas, FL Cosset, V Legros - Viruses, 2021 - mdpi.com
The Bunyavirales order comprises more than 500 viruses (generally defined as
bunyaviruses) classified into 12 families. Some of these are highly pathogenic viruses …
bunyaviruses) classified into 12 families. Some of these are highly pathogenic viruses …
Regulation of the Ebola virus VP24 protein by SUMO
S Vidal, A El Motiam, R Seoane, V Preitakaite… - Journal of …, 2019 - Am Soc Microbiol
Some viruses take advantage of conjugation of ubiquitin or ubiquitin-like proteins to
enhance their own replication. One example is Ebola virus, which has evolved strategies to …
enhance their own replication. One example is Ebola virus, which has evolved strategies to …
[HTML][HTML] Blocking tombusvirus replication through the antiviral functions of DDX17-like RH30 DEAD-box helicase
CY Wu, PD Nagy - PLoS Pathogens, 2019 - journals.plos.org
Positive-stranded RNA viruses replicate inside cells and depend on many co-opted cellular
factors to complete their infection cycles. To combat viruses, the hosts use conserved …
factors to complete their infection cycles. To combat viruses, the hosts use conserved …
The proteasomal Rpn11 metalloprotease suppresses tombusvirus RNA recombination and promotes viral replication via facilitating assembly of the viral replicase …
KR Prasanth, D Barajas, PD Nagy - Journal of virology, 2015 - Am Soc Microbiol
ABSTRACT RNA viruses co-opt a large number of cellular proteins that affect virus
replication and, in some cases, viral genetic recombination. RNA recombination helps …
replication and, in some cases, viral genetic recombination. RNA recombination helps …
Schlafen 11 restricts flavivirus replication
F Valdez, J Salvador, PM Palermo, JE Mohl… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT Schlafen 11 (Slfn11) is an interferon-stimulated gene that controls the synthesis
of proteins by regulating tRNA abundance. Likely through this mechanism, Slfn11 has …
of proteins by regulating tRNA abundance. Likely through this mechanism, Slfn11 has …
[HTML][HTML] Efficient production of Rift Valley fever virus-like particles: the antiviral protein MxA can inhibit primary transcription of bunyaviruses
M Habjan, N Penski, V Wagner, M Spiegel, AK Överby… - Virology, 2009 - Elsevier
Rift Valley fever virus (RVFV) is a highly pathogenic member of the family Bunyaviridae that
needs to be handled under biosafety level (BSL) 3 conditions. Here, we describe reverse …
needs to be handled under biosafety level (BSL) 3 conditions. Here, we describe reverse …
[HTML][HTML] Recent advances in Bunyavirus reverse genetics research: systems development, applications, and future perspectives
F Ren, S Shen, Q Wang, G Wei, C Huang… - Frontiers in …, 2021 - frontiersin.org
Bunyaviruses are members of the Bunyavirales order, which is the largest group of RNA
viruses, comprising 12 families, including a large group of emerging and re-emerging …
viruses, comprising 12 families, including a large group of emerging and re-emerging …
Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
Severe fever with thrombocytopenia syndrome is an emerging infectious disease caused by
a novel bunyavirus (SFTSV). Lack of vaccines and inadequate therapeutic treatments have …
a novel bunyavirus (SFTSV). Lack of vaccines and inadequate therapeutic treatments have …