Objectives The aim of this study was to determine the outcome of patients with severe sepsis
and septic shock who did and did not receive early goal-directed therapy (EGDT) in the …

BACKGROUND: Early goal-directed therapy (EGDT) has been shown to reduce mortality in
patients with severe sepsis/septic shock, however, implementation of this protocol in the …

Abstract Background The Surviving Sepsis Campaign has recommended early goal-
directed therapy (EGDT) as an essential strategy to decrease mortality among patients with …

Sepsis is a common and high-burden healthcare problem with a mortality exceeding 20% in
severe sepsis and nearly 50% when septic shock is present. Early goal-directed therapy …

Objective To determine the clinical effectiveness of implementing early goal-directed therapy
(EGDT) as a routine protocol in the emergency department (ED). Methods Prospective …

Objective To determine whether patients with severe sepsis or septic shock could benefit
from a strict and early goal-directed therapy (EGDT) protocol recommended by Surviving …

Study Objectives: Early goal directed therapy (EGDT) for the treatment of severe sepsis and
septic shock has been shown to decrease mortality. Recently, an EGDT protocol was …

Aims: The aim was to evaluate outcomes in patients with severe sepsis and septic shock
using EGDT in real life compared with patients who did not undergo it in the Intensive Care …

Purpose To assess the effects of early goal-directed therapy (EGDT) on reducing mortality
compared with conventional management of severe sepsis or septic shock. Materials and …

Results: A total of nine trails comprising 4783 patients included in our analysis. We found
that EGDT significantly reduced mortality in a random-effect model (RR, 0.86; 95 …