Introduction: Although it is a rare malignancy in the pediatric population, thyroid cancer, at
this stage of life, is associated with advanced stages of the disease when compared to …

Thyroid cancer is associated with a broad range of different mutations, including RET
(rearranged during transfection) fusion genes. The importance of characterizing RET fusion …

Introduction: Differentiated thyroid carcinoma (DTC) is rare in children, ranging from 0.3-
0.5% of all pediatric neoplasms. However, it remains the most common endocrine …

Objetivo: relatar aspectos clínico-patológicos do carcinoma papilífero de tireoide, associado
à fusão do gene RET, em criança submetida à tireoidectomia e radioiodoterapia adjuvante …

Abstract Disclosure: GJ Machado: None. AO Telles: None. JL von Ammon: None. RR da
Matta: None. FE Beltrão: None. F. Hecht: None. AR da Paz: None. GD Lopes: None. LF Rios …

Background We previously described mutation rates of BRAF V600E, RAS, RET-PTC and
PAX8-PPARγ in pediatric subjects with well-differentiated thyroid cancer (WDTC). We …

Introduction: Follicular-derived differentiated thyroid carcinoma (DTC) is the most common
endocrine and epithelial malignancy in children. The differences in the clinical and …

Background: Pediatric papillary thyroid carcinoma (PTC) is a rare malignancy, but with
increasing incidence. Pediatric PTCs have distinct clinical and pathological features and …

Abstract Objectives Differentiated thyroid cancers (DTCs) in the paediatric population differ
from that of their adult counterparts in terms of clinicopathological characteristics and …

Background RET rearrangements have emerged as a new actionable alteration in papillary
thyroid cancers (PTC). These fusions may involve many partner genes, are thought to be …