The learning of fear extinction

C Furini, J Myskiw, I Izquierdo - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Recent work on the extinction of fear-motivated learning places emphasis on its putative
circuitry and on its modulation. Extinction is the learned inhibition of retrieval of previously …

Modulation of the extinction of fear learning

JC Myskiw, I Izquierdo, CRG Furini - Brain research bulletin, 2014 - Elsevier
We review recent work on extinction learning with emphasis on its modulation. Extinction is
the learned inhibition of responding to previously acquired tasks. Like other forms of …

Test–retest reliability during fear acquisition and fear extinction in humans

MA Zeidan, K Lebron‐Milad… - CNS neuroscience & …, 2012 - Wiley Online Library
Aims: Classical fear conditioning and extinction has been used to understand the
neurobiology of fear learning and its inhibition. The recall of an extinction memory involves …

Fear memory

I Izquierdo, CRG Furini, JC Myskiw - Physiological reviews, 2016 - journals.physiology.org
Fear memory is the best-studied form of memory. It was thoroughly investigated in the past
60 years mostly using two classical conditioning procedures (contextual fear conditioning …

Amount of fear extinction changes its underlying mechanisms

B An, J Kim, K Park, S Lee, S Song, S Choi - Elife, 2017 - elifesciences.org
There has been a longstanding debate on whether original fear memory is inhibited or
erased after extinction. One possibility that reconciles this uncertainty is that the inhibition …

Role of the hippocampus and amygdala in the extinction of fear-motivated learning

MR Vianna, AS Coitinho… - Current neurovascular …, 2004 - ingentaconnect.com
Fear-motivated learning is at the root of phobias, panic, generalized anxiety and the
posttraumatic stress disorder. This makes the inhibition of fear-motivated behavior a …

Mechanisms of fear learning and extinction: synaptic plasticity–fear memory connection

NV Luchkina, VY Bolshakov - Psychopharmacology, 2019 - Springer
Rationale The ability to memorize threat-associated cues and subsequently react to them,
exhibiting escape or avoidance responses, is an essential, often life-saving behavioral …

Behavioral and neural analysis of extinction

KM Myers, M Davis - Neuron, 2002 - cell.com
The neural mechanisms by which fear is inhibited are poorly understood at the present time.
Behaviorally, a conditioned fear response may be reduced in intensity through a number of …

[HTML][HTML] A translational perspective on neural circuits of fear extinction: Current promises and challenges

D Sevenster, RM Visser, R D'Hooge - Neurobiology of Learning and …, 2018 - Elsevier
Fear extinction is the well-known process of fear reduction through repeated re-exposure to
a feared stimulus without the aversive outcome. The last two decades have witnessed a …

Fear extinction as a model for translational neuroscience: ten years of progress

MR Milad, GJ Quirk - Annual review of psychology, 2012 - annualreviews.org
The psychology of extinction has been studied for decades. Approximately 10 years ago,
however, there began a concerted effort to understand the neural circuits of extinction of fear …