Lipid nanoparticles (LNPs) have been one of the most successful nano-delivery vehicles
that enable efficient delivery of cytotoxic chemotherapy agents, antibiotics, and nucleic acid …

RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable
diseases and genetic disorders by regulating disease-related gene expression. The …

Gene therapy is an exciting field that has the potential to address emerging scientific and
therapeutic tasks. RNA-based gene therapy has made remarkable progress in recent …

In recent years, in vitro transcribed messenger RNA (mRNA) has emerged as a potential
therapeutic platform. To fulfill its promise, effective delivery of mRNA to specific cell types …

Conspectus After decades of extensive fundamental studies and clinical trials, lipid
nanoparticles (LNPs) have demonstrated effective mRNA delivery such as the Moderna and …

RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Introduction: Liposomes and lipid-based nanoparticles (LNPs) effectively deliver cargo
molecules to specific tissues, cells, and cellular compartments. Patients benefit from these …

Lipid nanoparticles (LNPs) are becoming popular as a means of delivering therapeutics,
including those based on nucleic acids and mRNA. The mRNA-based coronavirus disease …

Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

Messenger RNA (mRNA), which is composed of ribonucleotides that carry genetic
information and direct protein synthesis, is transcribed from a strand of DNA as a template …