Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1

M Arita, F Bianchini, J Aliberti, A Sher… - The Journal of …, 2005 - rupress.org
The essential fatty acid eicosapentaenoic acid (EPA) present in fish oils displays beneficial
effects in a range of human disorders associated with inflammation including cardiovascular …

[HTML][HTML] Resolvin D1 and its aspirin-triggered 17R epimer: stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation

YP Sun, SF Oh, J Uddin, R Yang, K Gotlinger… - Journal of Biological …, 2007 - ASBMB
We recently uncovered two new families of potent docosahexaenoic acid-derived mediators,
termed D series resolvins (Rv; resolution phase interaction products) and protectins. Here …

[HTML][HTML] The role of endogenous eicosapentaenoic acid and docosahexaenoic acid-derived resolvins in systemic sclerosis

A Avanoǧlu Güler, FW Rossi… - Frontiers in …, 2020 - frontiersin.org
Resolvins, the member of specialized pro-resolving mediators, are produced from omega-3
polyunsaturated fatty acids as a response to an acute inflammatory process in that …

[HTML][HTML] Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer

K Moro, M Nagahashi, R Ramanathan… - World journal of …, 2016 - ncbi.nlm.nih.gov
Inflammation is a central process in several disorders and contributes to cancer progression.
Inflammation involves a complex cascade of pro-inflammatory and anti-inflammatory …

Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation

M Arita, T Ohira, YP Sun, S Elangovan… - The Journal of …, 2007 - journals.aai.org
Abstract Resolvin E1 (RvE1) is a potent anti-inflammatory and proresolving mediator derived
from omega-3 eicosapentaenoic acid generated during the resolution phase of …

Omega-3 fatty acids and their lipid mediators: towards an understanding of resolvin and protectin formation

KH Weylandt, CY Chiu, B Gomolka… - Prostaglandins & other …, 2012 - Elsevier
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have long been associated with
decreased inflammation and are also implicated in the prevention of tumorigenesis …

The role of acetylated cyclooxygenase-2 in the biosynthesis of resolvin precursors derived from eicosapentaenoic acid

A Cebrián-Prats, A Pinto, À González-Lafont… - Organic & …, 2022 - pubs.rsc.org
Specialized pro-resolving lipid mediators (SPMs) are natural bioactive agents actively
involved in inflammation resolution. SPMs act when uncontrolled inflammatory processes …

Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids

MJ Zhang, M Spite - Annual review of nutrition, 2012 - annualreviews.org
Omega-3 polyunsaturated fatty acids (PUFAs) are essential to health, and deficiencies in
these PUFAs are linked to chronic disease. Although important insights into the diverse …

Resolvin E1 attenuates inj ury‐induced vascular neointimal formation by inhibition of inflammatory responses and vascular smooth muscle cell migration

G Liu, Y Gong, R Zhang, L Piao, X Li, Q Liu… - The FASEB …, 2018 - Wiley Online Library
Mechanical insults, such as stent implantation, can induce endothelial injury, vascular
inflammation, and ultimately lead to vascular neointimal hyperplasia. Resolvin E1 (RvE1) …

Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E3

Y Isobe, M Arita, R Iwamoto, D Urabe… - The journal of …, 2013 - academic.oup.com
Uncontrolled inflammation is now considered to be a link between many widely occurring
diseases. Thus, controlling the innate inflammatory response and its local chemical …