Inflammation is the first response of the immune system to infection or injury, but excessive
or inappropriate inflammatory responses contribute to a range of acute and chronic human …

Cardiovascular disease is an inflammatory process and the leading cause of death in the
United States. Novel omega-3 derived potent lipid mediators, termed resolvins and …

We recently demonstrated that ω-3-polyunsaturated fatty acids ameliorate obesity-induced
adipose tissue inflammation and insulin resistance. In this study, we report novel …

Abstract Resolvin E1 (RvE1; 5S, 12R, 18R-trihydroxy-6Z, 8E, 10E, 14Z, 16E-
eicosapentaenoic acid) is a potent anti-inflammatory and proresolving mediator derived from …

Acute inflammation resolution acts as a vital process for active host response, tissue support,
and homeostasis maintenance, during which resolvin D (RvD) and E (RvE) as mediators …

Research on the formation of novel enzymatic oxygenation products derived from the ω-3
fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) has revealed the …

Resolvin E1 (RvE1; 5 S, 12 R, 18 R-trihydroxyeicosapentaenoic acid) is an antiinflammatory
lipid mediator derived from omega-3 fatty acid eicosapentaenoic acid (EPA). At the local site …

Resolvins are endogenous lipid mediators that actively regulate the resolution of acute
inflammation. Resolvin E1 (RvE1;(5S, 12R, 18R)-trihydroxy-6Z, 8E, 10E, 14Z, 16E …

In the last decades, the development of new technologies applied to lipidomics has
revitalized the analysis of lipid profile alterations and the understanding of the underlying …

New classes of lipids such as lipoxins, resolvins, protectins and maresin are found to
promote the resolution of inflammation. The resolving actions of these endogenous lipids …