Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

In this review, we critically evaluate the case–control studies examining the relationship
between rheumatoid arthritis (RA) and periodontitis, two common chronic inflammatory …

The concept of focal infection or systemic disease arising from infection of the teeth was
generally accepted until the mid‐20th century when it was dismissed because of lack of …

This review aims to critically analyze the pathways of interaction and the pathogenic
mechanisms linking periodontitis and oral bacteria with the initiation/progression of cancer …

The past decade of basic research in periodontology has driven radical changes in our
understanding and perceptions of the pathogenic processes that drive periodontal tissue …

During the last two to three decades our understanding of the immunobiology of periodontal
disease has increased exponentially, both with respect to the microbial agents triggering the …

In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health.
Recent studies have provided insights into the emergence and persistence of dysbiotic oral …

Introduction: Periodontal diseases are the pathological manifestation of the host response
against the bacterial challenge from the dental biofilm at the tooth/gingival interface. The …

The purpose of this volume of PERIODONTOLOGY 2000 is to present the basic concepts
and facts constituting the current understanding of the pathogenesis of human periodontitis …