Uniformity of captopril benefit in the SAVE study: subgroup analysis

LA Moye, MA Pfeffer, CC Wun, BR Davis… - European heart …, 1994 - academic.oup.com
Abstract The Survival and Ventricular Enlargement (SAVE) Study demonstrated that long-
term administration of the angiotensin-converting enzyme inhibitor captopril to recent …

The Survival and Ventricular Enlargement (SAVE) study: rationale and perspective.

MA Pfeffer - Herz, 1993 - europepmc.org
Myocardial infarction increases the risk of subsequent cardiovascular events (eg, heart
failure or another myocardial infarction) among survivors as compared with the general …

Effects of captopril on ischemic events after myocardial infarction. Results of the Survival and Ventricular Enlargement trial. SAVE Investigators.

JD Rutherford, MA Pfeffer, LA Moye, BR Davis… - Circulation, 1994 - Am Heart Assoc
BACKGROUND In the Survival and Ventricular Enlargement (SAVE) trial, recurrent
myocardial infarction (MI) was the most important predictor of a poor outcome and conferred …

Cost-effectiveness of captopril therapy after myocardial infarction

J Tsevat, D Duke, L Goldman, MA Pfeffer… - Journal of the American …, 1995 - Elsevier
OBJECTIVES.: This study sought to assess the cost-effectiveness of captopril therapy for
survivors of myocardial infarction. BACKGROUND.: The recent randomized, controlled …

Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement …

MA Pfeffer, E Braunwald, LA Moyé… - New England journal …, 1992 - Mass Medical Soc
Background. Left ventricular dilatation and dysfunction after myocardial infarction are major
predictors of death. In experimental and clinical studies, long-term therapy with the …

Captopril: a review of its pharmacology and therapeutic efficacy after myocardial infarction and in ischaemic heart disease

GL Plosker, D McTavish - Drugs & Aging, 1995 - Springer
Synopsis Captopril is an angiotensin converting enzyme (ACE) inhibitor which has been
used extensively in the treatment of patients with hypertension and congestive heart failure …

Which patient benefits from early angiotensin-converting enzyme inhibition after myocardial infarction? Results of one-year serial echocardiographic follow-up from …

WH Van Gilst, JH Kingma, KH Peels… - Journal of the American …, 1996 - Elsevier
Objectives. In this study we sought to investigate the effect of intervention with captopril
within 6 h of the onset of myocardial infarction on left ventricular volume and clinical …

Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both

MA Pfeffer, JJV McMurray, EJ Velazquez… - … England Journal of …, 2003 - Mass Medical Soc
Background Angiotensin-converting–enzyme (ACE) inhibitors such as captopril reduce
mortality and cardiovascular morbidity among patients with myocardial infarction …

Cardiovascular death and left ventricular remodeling two years after myocardial infarction: baseline predictors and impact of long-term use of captopril: information …

MSJ Sutton, MA Pfeffer, L Moye, T Plappert… - Circulation, 1997 - Am Heart Assoc
Background We quantified cardiovascular death and/or left ventricular (LV) dilatation in
patients from the SAVE trial to determine whether dilatation continued beyond 1 year …

Angiotensin-converting enzyme inhibitors after myocardial infarction: indications and timing

SG Ball, AS Hall, GD Murray - Journal of the American College of …, 1995 - Elsevier
A number of major studies have examined the impact of angiotensin-converting enzyme
inhibitors on mortality in patients with ischemic heart disease. However, in these studies …