Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

JP Evans, C Zeng, C Carlin, G Lozanski… - Science Translational …, 2022 - science.org
The waning efficacy of SARS-CoV-2 vaccines, combined with the continued emergence of
variants resistant to vaccine-induced immunity, has reignited debate over the need for …

[HTML][HTML] Evidence for retained spike-binding and neutralizing activity against emerging SARS-CoV-2 variants in serum of COVID-19 mRNA vaccine recipients

JM Carreño, H Alshammary, G Singh, A Raskin… - …, 2021 - thelancet.com
Background Highly efficacious vaccines against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) have been developed. However, the emergence of viral …

[HTML][HTML] mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

WF Garcia-Beltran, KJS Denis, A Hoelzemer, EC Lam… - Cell, 2022 - cell.com
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.
1/B. 1.1. 529) harboring up to 36 mutations in spike protein, the target of neutralizing …

Two doses of the SARS-CoV-2 BNT162b2 vaccine enhance antibody responses to variants in individuals with prior SARS-CoV-2 infection

RA Urbanowicz, T Tsoleridis, HJ Jackson… - Science translational …, 2021 - science.org
Understanding the impact of prior infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) on the response to vaccination is a priority for responding to …

[HTML][HTML] SARS-CoV-2 mRNA vaccine induces robust specific and cross-reactive IgG and unequal neutralizing antibodies in naive and previously infected people

TM Narowski, K Raphel, LE Adams, J Huang, NA Vielot… - Cell reports, 2022 - cell.com
Understanding vaccine-mediated protection against severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) is critical to overcoming the global coronavirus disease 2019 …

[HTML][HTML] Neutralization of SARS-CoV-2 variants by mRNA and adenoviral vector vaccine-elicited antibodies

T Tada, H Zhou, MI Samanovic, BM Dcosta… - Frontiers in …, 2022 - frontiersin.org
The increasing prevalence of SARS-CoV-2 variants has raised concerns regarding possible
decreases in vaccine effectiveness. Here, neutralizing antibody titers elicited by mRNA …

Neutralizing antibodies to SARS‐CoV‐2 variants of concern including Delta and Omicron in subjects receiving mRNA‐1273, BNT162b2, and Ad26. COV2. S vaccines

GF Zhang, W Meng, L Chen, L Ding… - Journal of Medical …, 2022 - Wiley Online Library
SARS‐CoV‐2 vaccines have contributed to the control of COVID‐19 in some parts of the
world. However, the constant emergence of variants of concern (VOCs) challenges the …

[HTML][HTML] Durability of antibody response to vaccination and surrogate neutralization of emerging variants based on SARS-CoV-2 exposure history

TW McDade, AR Demonbreun, A Sancilio… - Scientific reports, 2021 - nature.com
Two-dose messenger RNA vaccines against the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) are highly effective in preventing symptomatic COVID-19 …

[HTML][HTML] Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

PR Wratil, M Stern, A Priller, A Willmann, G Almanzar… - Nature medicine, 2022 - nature.com
Infection-neutralizing antibody responses after severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 vaccination are an …

Assessment of neutralizing antibody response against SARS-CoV-2 variants after 2 to 3 doses of the BNT162b2 mRNA COVID-19 vaccine

K Furukawa, LH Tjan, Y Kurahashi… - JAMA network …, 2022 - jamanetwork.com
Importance Although 2 and 3 doses of vaccine have been implemented against the SARS-
CoV-2 pandemic, the level of immunity achieved by these additional vaccinations remains …