Functional and evolutionary analysis of DXL1, a non-essential gene encoding a 1-deoxy-D-xylulose 5-phosphate synthase like protein in Arabidopsis thaliana

L Carretero-Paulet, A Cairó, D Talavera, A Saura… - Gene, 2013 - Elsevier
The synthesis of 1-deoxy-D-xylulose 5-phosphate (DXP), catalyzed by the enzyme DXP
synthase (DXS), represents a key regulatory step of the 2-C-methyl-D-erythritol 4-phosphate …

Reassessing the evolution of the 1-deoxy-D-xylulose 5-phosphate synthase family suggests a possible novel function for the DXS class 3 proteins

L de Luna-Valdez, M Chenge-Espinosa… - Plant Science, 2021 - Elsevier
Abstract The methylerythritol 4-phosphate (MEP) pathway is of paramount importance for
generating plastidial isoprenoids. The first enzyme of the MEP pathway, 1-deoxy-D-xylulose …

Identification and characterization of class 1 DXS gene encoding 1-deoxy-d-xylulose-5-phosphate synthase, the first committed enzyme of the MEP pathway from …

M Zhang, K Li, C Zhang, J Gai, D Yu - Molecular biology reports, 2009 - Springer
Deoxy-d-xylulose-5-phosphate synthase (DXS) catalyses the first committed step of the 2C-
methyl-d-erythritol-4-phosphate (MEP) pathway, which is an alternative isoprenoids …

Exploring the Deoxy-D-xylulose-5-phosphate Synthase Gene Family in Tomato (Solanum lycopersicum)

X Di, M Rodriguez-Concepcion - Plants, 2023 - mdpi.com
Isoprenoids are a wide family of metabolites including high-value chemicals, flavors,
pigments, and drugs. Isoprenoids are particularly abundant and diverse in plants. The …

Two distantly related genes encoding 1‐deoxy‐d‐xylulose 5‐phosphate synthases: differential regulation in shoots and apocarotenoid‐accumulating mycorrhizal …

MH Walter, J Hans, D Strack - The Plant Journal, 2002 - Wiley Online Library
Isopentenyl diphosphate, the universal precursor of isoprenoids, is synthesized by two
separate routes, one in the cytosol and the other in plastids. The initial step of the plastidial …

Functional characterization of the three genes encoding 1-deoxy-D-xylulose 5-phosphate synthase in maize

E Cordoba, H Porta, A Arroyo… - Journal of …, 2011 - academic.oup.com
Abstract The 1-deoxy-d-xylulose 5-phosphate synthase (DXS) enzyme catalyses the first
biosynthetic step of the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway. In plants the …

Analysis of the Expression of CLA1, a Gene That Encodes the 1-Deoxyxylulose 5-Phosphate Synthase of the 2-C-Methyl-d-Erythritol-4-Phosphate Pathway in …

JM Estévez, A Cantero, C Romero, H Kawaide… - Plant …, 2000 - academic.oup.com
The discovery of the 2-C-methyl-d-erythritol-4-phosphate pathway for the biosynthesis of
isoprenoids raises the important question of the nature and regulation of the enzymes …

Albino T-DNA tomato mutant reveals a key function of 1-deoxy-D-xylulose-5-phosphate synthase (DXS1) in plant development and survival

M García-Alcázar, E Giménez, B Pineda, C Capel… - Scientific reports, 2017 - nature.com
Photosynthetic activity is indispensable for plant growth and survival and it depends on the
synthesis of plastidial isoprenoids as chlorophylls and carotenoids. In the non-mevalonate …

1-Deoxy-d-Xylulose 5-Phosphate Synthase (DXS), a Crucial Enzyme for Isoprenoids Biosynthesis

S Xiang, G Usunow, G Lange, M Busch… - Isoprenoid synthesis in …, 2013 - Springer
Isopentenyl pyrophosphate (IPP) and its isomer dimethylallyl pyrophosphate (DMAPP) are
the common precursors for the synthesis of all isoprenoids. While IPP and DMAPP are …

Essential role of residue H49 for activity of Escherichia coli 1-deoxy-D-xylulose 5-phosphate synthase, the enzyme catalyzing the first step of the 2-C-methyl-D …

J Querol, M Rodrı́guez-Concepción, A Boronat… - Biochemical and …, 2001 - Elsevier
The first step of the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway for isoprenoid
biosynthesis in plant plastids and most eubacteria is catalyzed by 1-deoxy-d-xylulose 5 …