From air pollution to cardiovascular diseases: the emerging role of epigenetics

MM Micheu, MV Birsan, R Szép, Á Keresztesi… - Molecular biology …, 2020 - Springer
The association between air pollution and a wide-ranging spectrum of acute and chronic
disorders—including cardiovascular diseases—is widely acknowledged. Exposure to …

Air pollution and epigenetics: recent findings

CV Breton, AN Marutani - Current environmental health reports, 2014 - Springer
The health effects of ambient air pollution are well-described, but less is known about the
biological mechanisms mediating these health effects. In recent years, the hypothesis that …

Gene–Air pollution interaction and cardiovascular disease: a review

A Zanobetti, A Baccarelli, J Schwartz - Progress in cardiovascular diseases, 2011 - Elsevier
Genetic susceptibility is likely to play a role in response to air pollution. Hence, gene-
environment interaction studies can be a tool for exploring the mechanisms and the …

Oxidative stress and inflammation mediate the effect of air pollution on cardio‐and cerebrovascular disease: a prospective study in nonsmokers

G Fiorito, J Vlaanderen, S Polidoro… - Environmental and …, 2018 - Wiley Online Library
Air pollution is associated with a broad range of adverse health effects, including mortality
and morbidity due to cardio‐and cerebrovascular diseases (CCVD), but the molecular …

Molecular mechanisms of environmental exposures and human disease

H Wu, CM Eckhardt, AA Baccarelli - Nature reviews genetics, 2023 - nature.com
A substantial proportion of disease risk for common complex disorders is attributable to
environmental exposures and pollutants. An appreciation of how environmental pollutants …

[HTML][HTML] Air pollution and epigenetics

A Syed, K Hew, A Kohli, G Knowlton… - Journal of Environmental …, 2013 - scirp.org
Air pollution is a global problem with far-reaching environmental impacts. Exposure has
been linked to a number of different adverse health effects. Understanding the impact of …

Epigenetic regulation in particulate matter-mediated cardiopulmonary toxicities: a systems biology perspective

T Wang, J GN Garcia, W Zhang - … and Personalized Medicine …, 2012 - ingentaconnect.com
Particulate matter (PM) air pollution exerts significant adverse health effects in global
populations, particularly in developing countries with extensive air pollution. Understanding …

A review of gene-by-air pollution interactions for cardiovascular disease, risk factors, and biomarkers

CK Ward-Caviness - Human genetics, 2019 - Springer
Air pollution is recognized as causal factor for cardiovascular disease (CVD) and is
associated with multiple CVD risk factors. Substantial research effort has been invested in …

Potential biological mediators of myocardial and vascular complications of air pollution—a state-of-the-art review

S Fathieh, SM Grieve, K Negishi, GA Figtree - Heart, Lung and Circulation, 2023 - Elsevier
Ambient air pollution is recognised globally as a significant contributor to the burden of
cardiovascular diseases. The evidence from both human and animal studies supporting the …

Short-term airborne particulate matter exposure alters the epigenetic landscape of human genes associated with the mitogen-activated protein kinase network: a cross …

JJ Carmona, T Sofer, J Hutchinson, L Cantone… - Environmental …, 2014 - Springer
Background Exposure to air particulate matter is known to elevate blood biomarkers of
inflammation and to increase cardiopulmonary morbidity and mortality. Major components of …