NP Samant, GL Gupta - European Journal of Neuroscience, 2021 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Aβ plaques and tauopathy are two major concerns associated …
M Michikawa - Molecular neurobiology, 2003 - Springer
The implication that cholesterol plays an essential role in the pathogenesis of Alzheimer's disease (AD) is based on the 1993 finding that the presence of apolipoprotein E (apoE) …
V Rudajev, J Novotny - Frontiers in molecular neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that is one of the most devastating and widespread diseases worldwide, mainly affecting the aging population. One …
E Staurenghi, S Giannelli, G Testa, B Sottero… - Antioxidants, 2021 - mdpi.com
In recent decades, the impairment of cholesterol metabolism in the pathogenesis of Alzheimer's disease (AD) has been intensively investigated, and it has been recognized to …
L Dai, L Zou, L Meng, G Qiang, M Yan, Z Zhang - Molecular neurobiology, 2021 - Springer
Cholesterol is an indispensable component of the cell membrane and plays vital roles in critical physiological processes. Brain cholesterol accounts for a large portion of total …
A Mathew, Y Yoshida, T Maekawa, DS Kumar - Brain research bulletin, 2011 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease manifested by cognitive and memory deterioration, culminating in a spectrum of neuropsychiatric …
Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disorder believed to be initiated by accumulation of amyloid β (Aβ)-related peptides derived from proteolytic …
FG Sagin, EY Sozmen - Current Alzheimer Research, 2008 - ingentaconnect.com
Advances in Alzheimer Disease (AD) research suggest that central nervous system (CNS) lipids play a key role in the pathogenesis. This role is attributed to the rich lipid content of …
M Wu, Y Zhai, X Liang, W Chen, R Lin, L Ma… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common cause of dementia, is a complex and multifactorial disease involving genetic and environmental factors, with …