7 Flexible probabilistic methods to unlock the clinical potential of liquid biopsy sampling

AP McDeed, S Jain, M McNamara… - Journal of Clinical and …, 2024 - cambridge.org
OBJECTIVES/GOALS: Decoding the origins of cell-free DNA (cfDNA) released from dying
cells in a liquid biopsy sample (eg blood) offers the potential to provide insight into the …

35 Novel statistical methods to unlock the clinical potential of liquid biopsy sampling

AP McDeed, S Jain, M Barefoot, J Ahn… - Journal of Clinical and …, 2023 - cambridge.org
OBJECTIVES/GOALS: Decoding the origins of cell-free DNA (cfDNA) released from dying
cells in a liquid biopsy sample (eg blood) can provide insight into the dynamic, organism …

Molecular profiling of liquid biopsies for precision oncology

EE Gonzalez-Kozlova - Computational Methods for Precision Oncology, 2022 - Springer
In recent years, the rapid development of next-generation sequencing (NGS) has led to a
significant increase in accuracy toward molecular profiling, allowing noninvasive and real …

Multimodality in liquid biopsy: does a combination uncover insights undetectable in individual blood analytes?

C Keup, R Kimmig, S Kasimir-Bauer - Journal of Laboratory Medicine, 2022 - degruyter.com
The heterogeneity of each individual oncologic disease can be mirrored by molecular
analysis of a simple blood draw in real time. Liquid biopsy testing has been shown useable …

[HTML][HTML] Epigenetic modifications of cfDNA in liquid biopsy for the cancer care continuum

J Wong, R Muralidhar, L Wang, CC Huang - Biomedical Journal, 2024 - Elsevier
This review provides a comprehensive overview of the latest advancements in the clinical
utility of liquid biopsy, with a particular focus on epigenetic approaches aimed at overcoming …

[引用][C] Optimizing Access to Liquid Biopsy in the Present and Future Cancer Landscape

AJ Medford, LW Ellisen - JCO Precision Oncology, 2024 - ascopubs.org
We discuss a recent manuscript providing recommendations to improve use and access for
liquid biopsy in oncology.

Liquid biopsy enters the clinic—implementation issues and future challenges

M Ignatiadis, GW Sledge, SS Jeffrey - Nature reviews Clinical oncology, 2021 - nature.com
Historically, studies of disseminated tumour cells in bone marrow and circulating tumour
cells in peripheral blood have provided crucial insights into cancer biology and the …

[HTML][HTML] Unlocking the promise of liquid biopsies in precision oncology

A Pando-Caciano, R Trivedi, J Pauwels… - The Journal of Liquid …, 2024 - Elsevier
Liquid biopsies have emerged as a promising and minimally invasive alternative to
traditional tissue biopsies for detecting and monitoring cancer. Liquid biopsies offer a …

Liquid Biopsy: Translating Minimally Invasive Disease Profiling from the Lab to the Clinic

D Zainfeld, U Ghani, I Kang, A Goldkorn - Precision Cancer Medicine …, 2019 - Springer
Precision medicine aims to characterize the unique molecular profile of individual tumors in
order to predict clinical course and inform therapeutic decisions. The success of this …

Pushing the Boundaries of Liquid Biopsies for Early Precision Intervention

V Anagnostou, VE Velculescu - Cancer discovery, 2024 - AACR
Liquid biopsies are emerging as powerful minimally invasive approaches that have the
potential to solve several long-standing problems spanning the continuum of cancer care …