Difficult-to-control asthma management in adults

A Menzies-Gow, WC Moore, ME Wechsler - The Journal of Allergy and …, 2022 - Elsevier
The management of difficult-to-control asthma remains a significant challenge, which
frequently requires the input of the wider multidisciplinary team. This review covers the …

Asthma management: are GINA guidelines appropriate for daily clinical practice?

BP Yawn, T van der Molen, M Humbert - Primary Care Respiratory Journal, 2005 - Elsevier
An international group of primary care asthma experts, as well as pulmonologists and
allergists from Europe and the US, met to discuss asthma management focused on the …

Phenotype-guided asthma therapy: an alternative approach to guidelines

L Perez de Llano, D Dacal Rivas… - Journal of Asthma …, 2021 - Taylor & Francis
Despite recent advances in therapy, a substantial proportion of asthmatics remain not well
controlled. The classical stepwise approach to pharmacological therapy in adult asthma …

Clinical asthma phenotypes in the real world: opportunities and challenges

C Bostantzoglou, V Delimpoura, K Samitas, E Zervas… - Breathe, 2015 - Eur Respiratory Soc
Key Points Asthma is a heterogeneous syndrome ranging from mild disease with barely
noticeable symptoms to very severe disease with constant symptoms that may greatly hinder …

Comorbid “treatable traits” in difficult asthma: current evidence and clinical evaluation

TR Tay, M Hew - Allergy, 2018 - Wiley Online Library
The care of patients with difficult‐to‐control asthma (“difficult asthma”) is challenging and
costly. Despite high‐intensity asthma treatment, these patients experience poor asthma …

[HTML][HTML] Personalised medicine in asthma: from curative to preventive medicine

L Guilleminault, H Ouksel, C Belleguic… - European …, 2017 - Eur Respiratory Soc
The concept of asthma has changed substantially in recent years. Asthma is now recognised
as a heterogeneous entity that is complex to treat. The subdivision of asthma, provided by …

Trait profiles in difficult‐to‐treat asthma: clinical impact and response to systematic assessment

T Lin, J Pham, E Denton, J Lee, F Hore‐Lacy… - Allergy, 2023 - Wiley Online Library
Background Multidisciplinary systematic assessment improves outcomes in difficult‐to‐treat
asthma, but without clear response predictors. Using a treatable‐traits framework, we …

Asthma outcomes workshop: overview

WW Busse, WJ Morgan, V Taggart, A Togias - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Asthma clinical research will highly benefit from standardization of major
outcomes in terms of definition and assessment methodology. This will permit useful …

Effectiveness of interventions targeting treatable traits for the management of obstructive airway diseases: a systematic review and meta-analysis

MR Sarwar, VM McDonald, MJ Abramson… - The Journal of Allergy …, 2022 - Elsevier
Background The management of obstructive airway diseases (OADs) is complex. The
treatable traits (TTs) approach may be an effective strategy for managing OADs. Objective …

[PDF][PDF] Treatable traits in asthma: moving beyond diagnostic labels

VM McDonald, PG Gibson - The Medical Journal of Australia, 2022 - mja.com.au
Asthma is a common inflammatory disease, affecting over 300 million people worldwide, 1
including one in nine Australian adults. 2 Asthma imposes a major burden on the health …