LncRNA UCA1 elevates the resistance of human leukemia cells to daunorubicin by the PI3K/AKT pathway via sponging miR-613

Q Yao, L Zhang, Y Wang, J Liu, L Yang… - Bioscience …, 2021 - portlandpress.com
Acute leukemia is a hematological malignant tumor. Long non-coding RNA urothelial cancer-
associated 1 (UCA1) is involved in the chemo-resistance of diverse cancers, but it is unclear …

Long non-coding RNA UCA1 modulates cell proliferation and apoptosis by regulating miR-296-3p/Myc axis in acute myeloid leukemia

J Li, M Wang, X Chen - Cell cycle, 2020 - Taylor & Francis
Acute myeloid leukemia (AML) is a common hematopoietic malignancy with a generally
poor prognosis. Long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) …

[PDF][PDF] Long noncoding RNA UCA1 promotes cell proliferation, migration and invasion of human leukemia cells via sponging miR-126.

MD Sun, YQ Zheng, LP Wang… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Acute myeloid leukemia (AML) is a bone marrow malignancy. Long non-coding
RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) plays an important role in several …

Long non-coding RNA UCA1 promotes cisplatin/gemcitabine resistance through CREB modulating miR-196a-5p in bladder cancer cells

J Pan, XU Li, W Wu, M Xue, H Hou, W Zhai, W Chen - Cancer letters, 2016 - Elsevier
Chemoresistance constitutes the major failing of clinical therapy for bladder cancer.
However, the molecular mechanisms involved in the chemoresistance of bladder cancer are …

lncRNA UCA1 mediates resistance to cisplatin by regulating the miR-143/FOSL2-signaling pathway in ovarian cancer

Z Li, H Niu, Q Qin, S Yang, Q Wang, C Yu, Z Wei… - … Therapy-Nucleic Acids, 2019 - cell.com
The aim of this study was to explore the roles of the long noncoding RNA (lncRNA) urothelial
carcinoma-associated 1 (UCA1) on cisplatin resistance in ovarian cancer and the underlying …

Knockdown of LncRNA‐UCA1 suppresses chemoresistance of pediatric AML by inhibiting glycolysis through the microRNA‐125a/hexokinase 2 pathway

Y Zhang, Y Liu, X Xu - Journal of cellular biochemistry, 2018 - Wiley Online Library
Dysregulation of lncRNAs is implicated in chemoresistance in varieties of tumor including
acute myeloid leukemia (AML). LncRNA urothelial carcinoma‐associated 1 (UCA1) was …

LncRNA UCA1 promotes proliferation and cisplatin resistance of oral squamous cell carcinoma by sunppressing miR‐184 expression

Z Fang, J Zhao, W Xie, Q Sun, H Wang… - Cancer …, 2017 - Wiley Online Library
Chemotherapy resistance has become the main obstacle for the effective treatment of
human cancers. Long non‐coding RNA urothelial cancer associated 1 (UCA 1) is generally …

Silencing of lncRNA UCA1 Reverses Doxorubicin Resistance of Breast Cancer Through Inhibiting PI3K/AKT/mTOR Signaling Pathway

M Suicmez, G Namalir, M Konus, H Ozdil - ChemistrySelect, 2024 - Wiley Online Library
The role of silencing of long non coding RNA UCA1 gene in the development of resistance
to doxorubicin in breast cancer was employed. We initially induced resistance to doxorubicin …

[HTML][HTML] LncRNA UCA1 in anti-cancer drug resistance

H Wang, Z Guan, K He, J Qian, J Cao, L Teng - Oncotarget, 2017 - ncbi.nlm.nih.gov
The pivotal role of the long non-coding RNA (lncRNA) urothelial carcinoma associated 1
(UCA1) in anti-cancer drug resistance has been confirmed in many cancers. Overexpression …

LncRNA UCA1 Enhances Cisplatin Resistance by Regulating CYP1B1-mediated Apoptosis via miR-513a-3p in Human Gastric Cancer

H Cheng, G Sharen, Z Wang, J Zhou - Cancer Management and …, 2021 - Taylor & Francis
Background Chemoresistance contributes to treatment failure of gastric cancer (GC) patients
but the molecular mechanism of chemoresistance in GC is still unclear. Long-chain …