[PDF][PDF] Leishmaniasis and Chagas disease–neglected tropical diseases: treatment updates

LS Sangenito, V da Silva Santos… - Current Topics in …, 2019 - academia.edu
The World Health Organization (WHO)[1] has listed 20 neglected tropical diseases (NTDs),
including infections caused by viruses, bacteria, fungi and protozoa. Together, these …

Leishmaniasis and Chagas disease chemotherapy: a critical review

I Silva-Jardim, OH Thiemann, FF Anibal - Journal of the Brazilian …, 2014 - SciELO Brasil
Leishmaniasis and Chagas disease, caused by the kinetoplastid parasites Leishmania spp
and Trypanosoma cruzi, respectively, are among the most important parasitic diseases …

[图书][B] Drug Discovery for Leishmaniasis

L Rivas, C Gil - 2017 - books.google.com
For human health, leishmaniasis is among the most important protozoan diseases,
superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million …

Current and promising novel drug candidates against visceral leishmaniasis

RM Reguera, Y Pérez-Pertejo… - Pure and Applied …, 2019 - degruyter.com
Leishmaniasis is a group of zoonotic diseases caused by a trypanosomatid parasite mostly
in impoverished populations of low-income countries. In their different forms, leishmaniasis …

An overview on the therapeutics of neglected infectious diseases—Leishmaniasis and Chagas diseases

K Chanda - Frontiers in Chemistry, 2021 - frontiersin.org
Neglected tropical diseases (NTDs) as termed by WHO include twenty different infectious
diseases that are caused by bacteria, viruses, and parasites. Among these NTDs, Chagas …

Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis

AS Nagle, S Khare, AB Kumar, F Supek… - Chemical …, 2014 - ACS Publications
Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …

Investigational drugs for visceral leishmaniasis

S Sundar, J Chakravarty - Expert opinion on investigational drugs, 2015 - Taylor & Francis
Introduction: The armamentarium of antileishmanial drugs is small. It is further being
threatened by the development of resistance and decreasing sensitivity to the available …

Advances and progress in Chagas disease drug discovery

LG Ferreira, MT de Oliveira… - Current topics in …, 2016 - ingentaconnect.com
Chagas disease represents a serious burden for millions of people worldwide. Transmitted
by the protozoan parasite Trypanosoma cruzi, this neglected tropical disease causes more …

Novel therapeutic strategies for treatment of visceral leishmaniasis

K Jain, NK Jain - Drug discovery today, 2013 - Elsevier
Highlights•Visceral leishmaniasis is a fatal infectious disease caused by protozoan
parasite.•Current antileishmanial drugs are inefficient for treatment of leishmaniasis.•There …

The kinetoplastid chemotherapy revisited: current drugs, recent advances and future perspectives

E Castillo, MA Dea-Ayuela… - Current medicinal …, 2010 - ingentaconnect.com
Leishmaniasis, African sleeping sickness and Chagas disease, caused by the kinetoplastid
parasites Leishmania spp, Trypanosoma brucei and Trypanosoma cruzi, respectively, are …