Primed for global coronavirus pandemic: Emerging research and clinical outcome

S Ahamad, S Branch, S Harrelson, MK Hussain… - European journal of …, 2021 - Elsevier
The global effort to combat and contain the coronavirus disease 2019 (COVID-19) caused
by the recently discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Immunological perspectives on the pathogenesis, diagnosis, prevention and treatment of COVID-19

Y Ni, A Alu, H Lei, Y Wang, M Wu, X Wei - Molecular biomedicine, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). COVID-19 can spread to …

Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection

BA Khalil, NM Elemam, AA Maghazachi - Computational and structural …, 2021 - Elsevier
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

Immunopathology and Immunopathogenesis of COVID-19, what we know and what we should learn

M Shahgolzari, A Yavari, Y Arjeini, SM Miri, A Darabi… - Gene reports, 2021 - Elsevier
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) directly interacts
with host's epithelial and immune cells, leading to inflammatory response induction, which is …

Discovering small-molecule therapeutics against SARS-CoV-2

V Tiwari, JC Beer, NV Sankaranarayanan… - Drug Discovery …, 2020 - Elsevier
Highlights•SARS-CoV-2's high homology with SARS-CoV did not prove beneficial
immediately.•Targeting viral attachment and fusion proteins has yielded good early …

SARS‐CoV‐2‐mediated immune system activation and potential application in immunotherapy

Y Tan, F Tang - Medicinal research reviews, 2021 - Wiley Online Library
Although novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐mediated
pulmonary inflammation has recently attracted great attention, its pathology and …

nCOVID-19 pandemic: from molecular pathogenesis to potential investigational therapeutics

MT Kabir, MS Uddin, MF Hossain… - Frontiers in cell and …, 2020 - frontiersin.org
In December 2019, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-
related epidemic was first observed in Wuhan, China. In 2020, owing to the highly infectious …

[HTML][HTML] A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies

CX Li, S Noreen, LX Zhang, M Saeed, PF Wu… - Biomedicine & …, 2022 - Elsevier
Coronavirus is a family of viruses that can cause diseases such as the common cold, severe
acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). The …

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …