Long‐Term Effects of Maternal Deprivation on Redox Regulation in Rat Brain: Involvement of NADPH Oxidase

B Marković, NV Radonjić, G Jevtić… - Oxidative Medicine …, 2017 - Wiley Online Library
Maternal deprivation (MD) causes perinatal stress, with subsequent behavioral changes
which resemble the symptoms of schizophrenia. The NADPH oxidase is one of the major …

Age-dependent effects of maternal deprivation on oxidative stress in infant rat brain

N Uysal, S Gonenc, O Acikgoz, Ç Pekçetin… - Neuroscience …, 2005 - Elsevier
Developing brain is much more sensitive to all kind of stressors than the developed brain.
Early maternal deprivation causes some behavioural and physiological effects on rats. After …

NADPH oxidase and redox status in amygdala, hippocampus and cortex of male Wistar rats in an animal model of post-traumatic stress disorder

R Petrovic, L Puskas, G Jevtic Dozudic, T Stojkovic… - Stress, 2018 - Taylor & Francis
Post-traumatic stress disorder (PTSD) is a highly prevalent and impairing disorder. Oxidative
stress is implicated in its pathogenesis. Nicotinamide adenine dinucleotide phosphate …

Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice

C Doverhag, M Keller, A Karlsson, M Hedtjarn… - Neurobiology of …, 2008 - Elsevier
BACKGROUND: Inflammation and reactive oxygen species (ROS) are important in the
development of perinatal brain injury. The ROS-generating enzyme NADPH oxidase (Nox2) …

Prenatal stress causes oxidative damage to mitochondrial DNA in hippocampus of offspring rats

L Song, J Zheng, H Li, N Jia, Z Suo, Q Cai, Z Bai… - Neurochemical …, 2009 - Springer
Mitochondrion, the primary source of reactive oxygen species (ROS), is also the target of
ROS. 8-Hydroxy-2′-deoxyguanosine (8-OH-dG) is the major end-product of damaged DNA …

The effect of prenatal stress on oxidative protein modification in the rat brain in ontogeny

AV V'yushina, AV Pritvorova, MA Flerov - Neurochemical Journal, 2012 - Springer
Oxidative protein modification (OPM) was studied in the striatum, hippocampus, and
hypothalamus of rats of various ages that were subjected to prenatal stress. The basal level …

Renal redox response to normal pregnancy in the rat

MW Cunningham Jr, JM Sasser… - American Journal of …, 2013 - journals.physiology.org
Normal pregnancy involves increased renal sodium reabsorption, metabolism, and oxygen
consumption, which can cause increased oxidative stress (OS). OS can decrease nitric …

Oxidative modification of proteins in brain structures in Sprague–Dawley rats and some behavioral parameters after prenatal stress

AV V'yushina, AV Pritvorova, MA Flerov - Neuroscience and Behavioral …, 2014 - Springer
The effects of late prenatal stress on free-radical oxidation of proteins in Sprague–Dawley
rats were studied in the cerebral cortex, striatum, hippocampus, and hypothalamus, along …

Reduced glutathione regenerating enzymes undergo developmental decline and sexual dimorphism in the rat cerebral cortex

VV Dukhande, AO Isaac, T Chatterji, JCK Lai - Brain research, 2009 - Elsevier
Oxidative stress during development may predispose humans to neurodegenerative
disorders in old age. Moreover, numerous ailments of brain disproportionately affect one of …

Regionally impaired redox homeostasis in the brain of rats subjected to global perinatal asphyxia: sustained effect up to 14 postnatal days

C Lespay-Rebolledo, R Perez-Lobos… - Neurotoxicity …, 2018 - Springer
The present report evaluates the effect of global perinatal asphyxia on several parameters of
oxidative stress and cell viability in rat brain tissue sampled at an extended neonatal period …