[HTML][HTML] Absence of mechanical allodynia and Aβ-fiber sprouting after sciatic nerve injury in mice lacking membrane-type 5 matrix metalloproteinase

K Komori, T Nonaka, A Okada, H Kinoh… - FEBS letters, 2004 - Elsevier
Matrix metalloproteinases (MMPs) are a family of endopeptidases that degrade extracellular
matrix components. Membrane-type 5 MMP (MT5-MMP/MMP-24) was identified as neuron …

Matrix metalloproteinases MMP‐2 and MMP‐9 in denervated muscle and injured nerve

Kherif, Dehaupas, Lafuma, Fardeau… - Neuropathology and …, 1998 - Wiley Online Library
Nerve crush or axotomy results in a transient or long‐term denervation accompanied by
remodelling in nerve, muscle and neuromuscular junctions. These changes include an …

Membrane-type 5 matrix metalloproteinase is expressed in differentiated neurons and regulates axonal growth

H Hayashita-Kinoh, H Kinoh, A Okada, K Komori, Y Itoh… - 2001 - AACR
Expression of membrane-type (MT) 5 matrix metalloproteinase (MMP) in the mouse brain
was examined. MT5-MMP was expressed in the cerebrum in embryos, but it declined after …

Extracellular matrix and matrix metalloproteinases in sciatic nerve

CI Platt, CA Krekoski, RV Ward… - Journal of …, 2003 - Wiley Online Library
Although matrix metalloproteinases (MMPs) are increasingly being implicated in several
pathologies of the nervous system, it is not yet clear what role they play in normal …

TNFα-induced MMP-9 promotes macrophage recruitment into injured peripheral nerve

VI Shubayev, M Angert, J Dolkas, WM Campana… - Molecular and Cellular …, 2006 - Elsevier
Matrix metalloproteinase-9 (MMP-9) is an extracellular protease that is induced hours after
injury to peripheral nerve. This study shows that MMP-9 gene deletion and neutralization …

Elevated matrix metalloproteinase 9 supports peripheral nerve regeneration via promoting Schwann cell migration

P Lu, G Wang, X Lu, P Qiao, Y Jin, J Yu, Q Chen… - Experimental …, 2022 - Elsevier
Matrix metalloproteinases (MMPs) are important contributing factors of tissue remodeling
and wound healing. MMP9, a predominant soluble MMP, has been discovered as one of the …

Cytokine regulation of MMP-9 in peripheral glia: implications for pathological processes and pain in injured nerve

S Chattopadhyay, RR Myers, J Janes… - Brain, behavior, and …, 2007 - Elsevier
Matrix metalloproteinase-9 (MMP-9) is an extracellular protease that is induced in Schwann
cells hours after peripheral nerve injury and controls axonal degeneration and macrophage …

MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage

H Kobayashi, S Chattopadhyay, K Kato… - Molecular and Cellular …, 2008 - Elsevier
Matrix metalloproteinases (MMPs) emerge as modulators of neuropathic pain. Because
myelin protects Aβ afferents from ectopic hyperexcitability and nociception from innocuous …

[HTML][HTML] Spatial and temporal analysis of nociception-related spinal cord matrix metalloproteinase expression in a murine neuropathic pain model

JT Liou, DCW Sum, FC Liu, CC Mao, YS Lai… - Journal of the Chinese …, 2013 - Elsevier
BACKGROUND: Although the mammalian central nervous system contains numerous matrix
metalloproteinases (MMPs), the significance of each MMP relative to nociception remains …

Matrix metalloproteinase‐2 is involved in myelination of dorsal root ganglia neurons

HC Lehmann, A Köhne, F Bernal, P Jangouk… - Glia, 2009 - Wiley Online Library
Matrix metalloproteinases (MMPs) comprise a large family of endopeptidases that are
capable of degrading all extracellular matrix components. There is increasing evidence that …