Matrix metalloproteinase mediated degradation of basement membrane proteins in Trembler J neuropathy nerves

A Misko, T Ferguson, L Notterpek - Journal of neurochemistry, 2002 - Wiley Online Library
A single point mutation in peripheral myelin protein 22 (pmp22) of the Trembler‐J (TrJ)
mouse models the human peripheral neuropathy, Charcot–Marie–Tooth disease type 1 A …

Reciprocal relationship between membrane type 1 matrix metalloproteinase and the algesic peptides of myelin basic protein contributes to chronic neuropathic pain

S Hong, AG Remacle, SA Shiryaev, W Choi… - Brain, behavior, and …, 2017 - Elsevier
Myelin basic protein (MBP) is an auto-antigen able to induce intractable pain from
innocuous mechanical stimulation (mechanical allodynia). The mechanisms provoking this …

Neural MMP‐28 expression precedes myelination during development and peripheral nerve repair

SR Werner, AL Mescher, AW Neff… - … dynamics: an official …, 2007 - Wiley Online Library
Abstract Mammalian matrix metalloproteinase 28 (MMP‐28) is expressed in several normal
adult tissues, and during cutaneous wound healing. We show that, in frog and mouse …

Acute-and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury

AG Remacle, SK Hullugundi, J Dolkas… - Journal of …, 2018 - Springer
Background In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9
performs essential functions in the acute response to injury. Whether MMP-9 activity …

Distinct roles of matrix metalloproteases in the early-and late-phase development of neuropathic pain

Y Kawasaki, ZZ Xu, X Wang, JY Park, ZY Zhuang… - Nature medicine, 2008 - nature.com
Abstract Treatment of neuropathic pain, triggered by multiple insults to the nervous system,
is a clinical challenge because the underlying mechanisms of neuropathic pain …

Expression of matrix metalloproteinases in the neurogenic niche of the adult monkey hippocampus after ischemia

L Lu, AB Tonchev, DB Kaplamadzhiev… - …, 2008 - Wiley Online Library
Abstract Matrix metalloproteinases (MMPs), zinc‐dependent endopeptidases capable of
remodeling extracellular matrix and regulating cellular signals, have been implicated in …

Differential expression of tissue inhibitor of metalloproteinases‐3 in cultured astrocytes and neurons regulates the activation of matrix metalloproteinase‐2

W Liu, T Furuichi, M Miyake… - Journal of …, 2007 - Wiley Online Library
Matrix metalloproteinases (MMPs) degrade the extracellular matrix and are implicated in the
pathogenesis of several neurological diseases. Secreted in proforms, the MMPs require …

Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and-12 null mice

PH Larsen, AG DaSilva, K Conant… - Journal of …, 2006 - Soc Neuroscience
The matrix metalloproteinases (MMPs) are implicated in several activities within the nervous
system. Although many functions of abnormally elevated MMPs are undesirable, the discrete …

Different expression of tissue inhibitor of metalloproteinase family members in rat dorsal root ganglia and their changes after peripheral nerve injury

B Huang, X Zhao, LB Zheng, L Zhang, B Ni, YW Wang - Neuroscience, 2011 - Elsevier
Matrix metalloproteinase 9 (MMP9) and MMP2 are important in the development and
maintenance of neuropathic pain behavior induced by peripheral nerve injury. The …

Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain‐specific MMP highly expressed in cerebellum

Y Sekine‐Aizawa, E Hama, K Watanabe… - European Journal of …, 2001 - Wiley Online Library
The matrix metalloproteinase (MMP) family, comprising more than 20 isoforms, modulates
the extracellular milieu by degrading extracellular matrix (ECM) proteins. Because MMP is …