Tissue inhibitors of metalloproteinases (TIMPs) are a family of closely related proteins that
inhibit matrix metalloproteinases (MMPs). In the central nervous system (CNS), TIMPs 2, 3 …

Matrix metalloproteinases (MMPs) are a family of Zn2+ endopeptidases that are expressed
in many inflammatory conditions and that contribute to connective tissue breakdown and the …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in both injury
and repair mechanisms in the CNS. Pharmacological blockade of MMPs, limited to the first …

Abstract Matrix metalloproteinases (MMPs) are Zn 2+-dependent endopeptidases
considered to be essential for normal brain development and neuroplasticity by modulating …

Naı̈ve monocytes extravasate in response to monocyte chemoattractant-1 (MCP-1) and
subsequently, following differentiation within tissue, carry out effector functions. Consistent …

The matrix metalloproteinases (MMPs) are a large family of zinc-dependent enzymes which
are able to degrade the protein components of the extracellular matrix. They can be placed …

Injury to peripheral nerve initiates a degenerative process that converts the denervated
nerve from a suppressive environment to one that promotes axonal regeneration. We …

Matrix metalloproteinases (MMPs) are proteases known for their capacity to degrade
extracellular matrix (ECM) components. MMPs have been implicated in several central …

Membrane-type 3 matrix metalloproteinase (MT3-MMP) is a novel MT-MMP which has a
transmembrane domain at the C terminus, and mediates activation of pro-gelatinase A, just …

An increasing body of data has shown that matrix metalloproteinase-9 (MMP-9), an
extracellularly acting, Zn2+-dependent endopeptidase, is important not only for pathologies …