Mouse matrix metalloprotease‐1a (Mmp1a) gives new insight into MMP function

CJ Foley, A Kuliopulos - Journal of cellular physiology, 2014 - Wiley Online Library
Matrix metalloprotease‐1 (MMP1) has been implicated in many human disease processes,
however the lack of a well characterized murine homologue has significantly limited the …

The 84‐kDa form of human matrix metalloproteinase‐9 degrades substance P and gelatin

JR Backstrom, ZA Tökés - Journal of neurochemistry, 1995 - Wiley Online Library
Matrix metalloproteinase‐9 (MMP‐9) is secreted from cells and, once activated, is thought to
degrade collagen in the extracellular matrix. Because collagen is not readily localized where …

MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy

D Martins, J Moreira, NP Gonçalves… - Disease models & …, 2017 - journals.biologists.com
Levels of matrix metalloproteases (MMPs) can be differentially regulated in response to
injury or neurological diseases. For instance, it is known that selective and short-term …

Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke

S Lenglet, F Montecucco, F Mach… - Thrombosis and …, 2014 - thieme-connect.com
Matrix metalloproteinases (MMPs) are a family of more than twenty secreted and cell-surface
endopeptidases. Among them, MMP2, MMP3 and MMP9 are involved in blood-brain barrier …

Matrix metalloproteinases and their inhibitors in human traumatic spinal cord injury

A Buss, K Pech, BA Kakulas, D Martin, J Schoenen… - BMC neurology, 2007 - Springer
Abstract Background Matrix metalloproteinases (MMPs) are a family of extracellular
endopeptidases that degrade the extracellular matrix and other extracellular proteins …

The up-regulation of stromelysin-1 (MMP-3) in a spontaneously demyelinating transgenic mouse precedes onset of disease

CA D'Souza, B Mak, MA Moscarello - Journal of Biological Chemistry, 2002 - ASBMB
The matrix metalloproteinases (MMPs) are a family of endoproteinases that degrade various
components of the extracellular matrix and have been implicated in the pathogenesis of …

MMPs in the central nervous system: where the good guys go bad

SM Agrawal, L Lau, VW Yong - Seminars in cell & developmental biology, 2008 - Elsevier
Matrix metalloproteinases (MMPs) are expressed in the developing, healthy adult and
diseased CNS. We emphasize the regulation of neurogenesis and oligodendrogenesis by …

Upregulation of matrix metalloproteinase-9/2 in the wounded tissue, dorsal root ganglia, and spinal cord is involved in the development of postoperative pain

HW Gu, F Xing, MJ Jiang, Y Wang, L Bai, J Zhang… - Brain Research, 2019 - Elsevier
Emerging evidence implicates the upregulation of matrix metalloproteinase (MMP)-9/2 in the
dorsal root ganglion (DRG) and spinal cord as a contributor to the pathogenesis of chronic …

Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP

D Pei - Journal of Biological Chemistry, 1999 - ASBMB
A new member of the membrane-type matrix metalloproteinase (MT-MMP) subfamily
tentatively named MT5-MMP was isolated from mouse brain cDNA library. It is predicted to …

Collagenase-2 deficiency or inhibition impairs experimental autoimmune encephalomyelitis in mice

AR Folgueras, A Fueyo, O Garcia-Suarez, J Cox… - Journal of Biological …, 2008 - ASBMB
Matrix metalloproteinases (MMPs) have been implicated in a variety of human diseases,
including neuroimmunological disorders such as multiple sclerosis. However, the recent …