The current standard treatment of chronic heart failure (HF) is based on clinical judgment,
with the goal of achieving the maximally tolerated therapeutic program. The complexity of …

The management of heart failure remains challenging despite many therapeutic advances.
Rigorous clinical trial evidence supports administration of multiple therapies, but utilization …

The last two centuries have witnessed countless discoveries in the field of medicine that
found their roots in the up growing development of technology as well as in the visionary …

Natriuretic peptides play a crucial role in maintaining cardiovascular homeostasis. Among
their properties are vasodilation, natriuresis, diuresis, and inhibition of cardiac remodeling …

Following the initial discovery of a natriuretic and diuretic peptide factor present in atrial
myocardial tissue homogenates, subsequent elucidation of the natriuretic peptide (NP) …

Heart failure is a clinical syndrome of signs and symptoms caused by left ventricular
dysfunction. It is the most serious expression of heart disease and encompasses a wide …

Since the discovery of atrial natriuretic peptide, the unravelling of the natriuretic peptide
system has been a story of scientific success. However, bridging the gap between bench …

Natriuretic peptides (NPs) counter the effects of volume overload or adrenergic activation of
the cardiovascular system. They are able to induce arterial vasodilatations, natriuresis and …

BACKGROUND: Measurement of circulating natriuretic peptides has been shown to play an
important role in diagnosis and prognosis in patients with chronic heart failure. Whether …

BACKGROUND Heart failure (HF) is a complex syndrome with an enormous societal burden
in terms of cost and morbidity and mortality. Natriuretic peptide (NP) testing is now widely …