Science for surgeons: understanding pump thrombogenesis in continuous-flow left ventricular assist devices

AR De Biasi, KB Manning, A Salemi - The Journal of Thoracic and …, 2015 - jtcvs.org
Left ventricular assist devices (LVADs) have emerged as a mainstay, lifesaving treatment
option for patients with refractory heart failure, with 1-and 2-year actuarial survival rates of …

Limited efficacy of thrombolytics for pump thrombosis in durable left ventricular assist devices

L Seese, G Hickey, M Keebler, F Thoma… - The Annals of Thoracic …, 2020 - Elsevier
Background This study reports a single-center experience with thrombolytics for left
ventricular assist device (LVAD) pump thrombosis. Methods Adults undergoing continuous …

[HTML][HTML] Continuous-flow left ventricular assist device thrombosis: a danger foreseen is a danger avoided

J Fatullayev, M Samak, A Sabashnikov… - … science monitor basic …, 2015 - ncbi.nlm.nih.gov
Left ventricular assist devices (LVAD) are an increasingly implemented therapeutic
intervention for patients with end-stage heart failure. A growing body of evidence, however …

Medical management of pump-related thrombosis in patients with continuous-flow left ventricular assist devices: a systematic review and meta-analysis

G Dang, N Epperla, V Muppidi, N Sahr, A Pan… - Asaio …, 2017 - journals.lww.com
Pump thrombosis is a dreaded complication of left ventricular assist devices (LVADs). We
completed a systematic review to evaluate the efficacy and complications associated with …

Mechanisms of bleeding and approach to patients with axial-flow left ventricular assist devices

J Suarez, CB Patel, GM Felker, R Becker… - Circulation: Heart …, 2011 - Am Heart Assoc
During the past several decades, left ventricular assist devices (LVADs) have become a
valuable therapeutic option in the management of advanced systolic heart failure. Durable …

Pump thrombosis redux

GC Stewart, MM Givertz, MR Mehra - The Journal of Heart and Lung …, 2015 - jhltonline.org
Left ventricular assist devices (LVADs) are now a durable mainstay of therapy for medically
refractory advanced heart failure (HF). 1 Continuous-flow LVADs demonstrated increased …

Future developments in left ventricular assist device therapy

A Shaffer, R Cogswell, R John - The Journal of Thoracic and …, 2021 - jtcvs.org
Feature Editor's Introduction—Durable left ventricular assist device (LVAD) therapy has had
a remarkable evolution over the past 2 decades. Moving from a therapy once confined to …

Management of pump thrombosis in patients with left ventricular assist devices

JM Stulak, S Sharma, S Maltais - American Journal of Cardiovascular …, 2015 - Springer
The gradual evolution of left ventricular assist device (LVAD) therapy has resulted in a
durable option for patients as either a bridge to transplantation (BTT) or a destination …

What is the truth behind pump thrombosis in the HeartMate II device? A National Heart, Lung, and Blood Institute perspective based on data from the Interagency …

N Jeffries, MA Miller, WC Taddei-Peters… - The Journal of Heart …, 2015 - jhltonline.org
The clinical community faces major issues in caring for the 100,000 to 300,000 advanced
heart failure patients in the United States. 1 For these patients, left ventricular assist devices …

Haemolysis as a first sign of thromboembolic event and acute pump thrombosis in patients with the continuous-flow left ventricular assist device HeartMate II

S Akin, OI Soliman, AA Constantinescu, F Akca… - Netherlands Heart …, 2016 - Springer
Background Despite advances in pump technology, thromboembolic events/acute pump
thrombosis remain potentially life-threatening complications in patients with continuous-flow …